Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972343 | 0.78 | ENO1 (0.40) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL12639204 | 0.72 | CYP17A1 (0.55) | MEN1KMT2ASMN1; SMN2L3MBTL1CA12 | |
| SCHEMBL10807128 | 0.71 | LMNA (0.47) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL11079024 | 0.70 | TSHR (0.49) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL19306519 | 0.70 | KLK7 (0.41) | MEN1KMT2ASMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL7558962 | 0.69 | LMNA (0.59) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL7520078 | 0.68 | KMT2A (0.44) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL28992402 | 0.68 | SMN1; SMN2 (0.44) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL4404861 | 0.67 | IDO1 (0.57) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL30880316 | 0.67 | MEN1 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173414-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064864-A9 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 2001-12-27 | — | — | WO | disclosed |
| WO-2000064864-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |