Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENO1 | P06733 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560664 | 0.87 | ALDH1A1 (0.39) | ENO1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7608786 | 0.85 | ENO1 (0.44) | ENO1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7604170 | 0.79 | HTR2A (0.51) | ENO1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7556391 | 0.79 | ENO1 (0.42) | ENO1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7559753 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7557486 | 0.78 | CA12 (0.42) | ENO1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL16358394 | 0.74 | ENO1 (0.52) | ENO1ALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7520078 | 0.73 | KMT2A (0.44) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL16358054 | 0.72 | ENO1 (0.49) | ENO1ALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL29071595 | 0.72 | ENO1 (0.53) | ENO1ALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000064864-A9 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 2001-12-27 | — | — | WO | disclosed |