Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | GCG | P01275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746992 | 0.82 | CYP2C19 (0.50) | ALDH1A1NPSR1CYP2C19FFAR4FFAR1 | |
| SCHEMBL29037321 | 0.76 | CYP2C19 (0.46) | CYP2C19NR4A2PDCD1CD274NOTUM | |
| SCHEMBL13824212 | 0.76 | NR4A2 (0.44) | CYP2C19NR4A2FFAR4FFAR1PDCD1 | |
| SCHEMBL5907399 | 0.74 | FOLH1 (0.49) | ALDH1A1FFAR4FFAR1PDCD1CD274 | |
| SCHEMBL9988740 | 0.74 | NR4A2 (0.45) | CYP2C19NR4A2FFAR4FFAR1PDCD1 | |
| SCHEMBL1497158 | 0.74 | CYP2C19 (0.53) | CYP2C19NR4A2FFAR4FFAR1PDCD1 | |
| SCHEMBL2389062 | 0.73 | NR4A2 (0.44) | CYP2C19NR4A2FFAR4FFAR1PDCD1 | |
| SCHEMBL1154775 | 0.71 | AHR (0.44) | ALDH1A1CYP2C19PDCD1CD274 | |
| SCHEMBL2647050 | 0.71 | ALDH1A1 (0.39) | ALDH1A1NPSR1CYP2C19FFAR4FFAR1 | |
| SCHEMBL5009050 | 0.71 | SLC6A3 (0.55) | CYP2C19FFAR4FFAR1SUCNR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020111486-A1 | Transition metal-cyclopentadienyl-tropane conjugates | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111486-A1 | Transition metal-cyclopentadienyl-tropane conjugates | SLC6A3, SLC18A2, SLC6A2 | ALDH1A1 231/4885NPSR1 272/4885CYP2C19 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.