SCHEMBL755982

SCHEMBL755982

OC(O)C(O)C(O)Cc1cnc(CC(O)C(O)C(O)O)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706459 0.81 KDM4E (0.36)
SCHEMBL8339346 0.70 L3MBTL1 (0.35)
SCHEMBL8342917 0.70 L3MBTL1 (0.35)
SCHEMBL8339279 0.70 L3MBTL1 (0.35)
SCHEMBL8343219 0.70 L3MBTL1 (0.35)
SCHEMBL7657084 0.68 HSD17B10 (0.36)
SCHEMBL7656655 0.68 HSD17B10 (0.36)
SCHEMBL6740679 0.68 LMNA (0.32)
SCHEMBL6741902 0.68 LMNA (0.32)
SCHEMBL7657132 0.68 HSD17B10 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9592202-B2 Method to stabilize a dietary supplement to facilitate joint health in humans WYETH LLC (US) 2017-03-14 US disclosed
EP-2429500-B1 METHOD TO STABILIZE A DIETARY SUPPLEMENT COMPRISING GLUCOSAMINE WYETH LLC (US) 2015-01-14 EP disclosed
EP-2429500-A1 METHOD TO STABILIZE A DIETARY SUPPLEMENT COMPRISING GLUCOSAMINE Wyeth LLC (US) 2012-03-21 EP disclosed
WO-2010141191-A1 METHOD TO STABILIZE A DIETARY SUPPLEMENT COMPRISING GLUCOSAMINE WYETH LLC (US) 2010-12-09 WO disclosed
US-20100291240-A1 Method to Stabilize a Dietary Supplement to Facilitate Joint Health in Humans WYETH LLC (US) 2010-11-18 US disclosed
EP-1704862-A1 2,5-bis(tetrahydroxybutyl)pyrazines for the treatment of osteoarthritis and rheumatoid arthritis Rottapharm S.p.A. (IT) 2006-09-27 EP disclosed
EP-1704862-A1 2,5-bis(tetrahydroxybutyl)pyrazines for the treatment of osteoarthritis and rheumatoid arthritis Rottapharm S.p.A. (IT) 2006-09-27 EP disclosed
US-20020051828-A1 Mixtures which can be isolated from eugenia jambolana lamarck seeds, their preparation and the use of these mixtures and some of their constituents as medicaments RHONE-POULENC RORER S.A. AND INSTITUT MALGACHE DE RECHERCHES APPLIQUEES 2002-05-02 US disclosed
US-6300375-B1 ADMINISTERING SODIUM OXAMATE FOR PROPHYLAXIS OR THERAPY OF DIABETES OR COMPLICATIONS DUE TO DIABETES RHONE-POULENC RORER SA (FR) 2001-10-09 US disclosed
EP-0879058-B1 MIXTURES DERIVED FROM GRAINS OF EUGENIA JAMBOLANA LAMARCK, PREPARATION AND USE OF SAID MIXTURES AND SOME OF THEIR CONSTITUENTS AS MEDICAMENTS INST MALGACHE DE RECH S APPLIQ (MG) 2001-06-06 EP disclosed
US-6194412-B1 ANTIDIABETIC AGENTS RHONE-POULENC RORER S.A. (FR) 2001-02-27 US disclosed
US-5972342-A ANTIDIABETIC AGENTS RHONE-POULENC RORER S.A. (FR) 1999-10-26 US disclosed
EP-0879058-A1 MIXTURES DERIVED FROM GRAINS OF EUGENIA JAMBOLANA LAMARCK, PREPARATION AND USE OF SAID MIXTURES AND SOME OF THEIR CONSTITUENTS AS MEDICAMENTS Institut Malgache de Recherches Appliquées (MG) 1998-11-25 EP disclosed
WO-1997028813-A1 MIXTURES DERIVED FROM GRAINS OF EUGENIA JAMBOLANA LAMARCK, PREPARATION AND USE OF SAID MIXTURES AND SOME OF THEIR CONSTITUENTS AS MEDICAMENTS INSTITUT MALGACHE DE RECHERCHES APPLIQUEES (MG) 1997-08-14 WO disclosed