SCHEMBL756003

SCHEMBL756003

Cc1cc2cc3cc(Br)c(-c4cc(Cl)c(-c5cc6cc7cc(C)c(C)cc7cc6cc5Br)cc4Cl)cc3cc2cc1C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.39
AHR P35869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL752710 0.87 TERT (0.33) MAPK1
SCHEMBL754915 0.84 CYP3A4 (0.32) MAPK1
SCHEMBL756006 0.78
SCHEMBL811102 0.71 AHR (0.40) MAPK1AHR
SCHEMBL15131714 0.71 TERT (0.39) MAPK1
SCHEMBL2347027 0.69 TSHR (0.38) MAPK1
SCHEMBL811040 0.69 CD44 (0.39) MAPK1AHR
SCHEMBL120843 0.69 BCHE (0.37) MAPK1
SCHEMBL19785387 0.69 AHR (0.50) MAPK1AHR
SCHEMBL4282887 0.69 AHR (0.46) MAPK1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138355-B2 Heteroacene derivative, tetrahaloterphenyl derivative, and processes for producing the same TOSOH CORPORATION (JP) 2012-03-20 US disclosed
US-20090261300-A1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING THE SAME TOSOH CORPORATION (JP) 2009-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090261300-A1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING THE SAME AS3MT, TERT, TEAD1 MAPK1 951/4885AHR 544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.