Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6041374 | 0.92 | SLC6A4 (0.42) | SLC6A3SLC6A2SLC6A4CHRM2CHRM4 | |
| SCHEMBL6041266 | 0.82 | SLC6A3 (0.41) | SLC6A3SLC6A2SLC6A4CHRM2CHRM4 | |
| SCHEMBL7952076 | 0.71 | CHRM1 (0.41) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9243087 | 0.66 | SLC6A3 (0.54) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6991525 | 0.65 | SIGMAR1 (0.36) | SLC6A3SLC6A4CHRM1 | |
| SCHEMBL2190026 | 0.65 | CHRM1 (0.54) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL2190030 | 0.65 | CHRM1 (0.54) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6043904 | 0.64 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL857819 | 0.64 | CHRM1 (0.38) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL12507091 | 0.62 | CHRM1 (0.37) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |