Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.44 |
| ▸ | LPL | P06858 | 6/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558785 | 1.00 | TYR (0.47) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL7557949 | 0.82 | ALOX5 (0.54) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL9493209 | 0.81 | LIPG (0.49) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL5722768 | 0.79 | ALOX5 (0.54) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL5722737 | 0.78 | TYR (0.35) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL7931977 | 0.77 | LPL (0.47) | CYP3A4TP53LIPGLPLTRPV1 | |
| SCHEMBL7920088 | 0.77 | LPL (0.47) | CYP3A4TP53LIPGLPLTRPV1 | |
| SCHEMBL7563652 | 0.74 | ALOX5 (0.48) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL7557837 | 0.74 | RARB (0.45) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL6291363 | 0.73 | LIPG (0.59) | TYRCYP3A4MAPTMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944565-B1 | 1,3,5-TRIFLUORONAPHTHALENE DERIVATIVES FOR LIQUID CRYSTALLINE MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2002-07-31 | — | — | EP | disclosed |