Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6041390 | 0.92 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL7568319 | 0.90 | CHRM2 (0.40) | CHRM2CHRM4CHRM1CHRM3DPP4 | |
| SCHEMBL6042198 | 0.82 | CHRM2 (0.40) | CHRM2CHRM4CHRM1CHRM3MAPK1 | |
| SCHEMBL6042563 | 0.76 | CHRM2 (0.37) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL7553812 | 0.68 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL6041346 | 0.68 | CCR1 (0.37) | MDM2 | |
| SCHEMBL6043236 | 0.65 | REN (0.42) | — | |
| SCHEMBL6042380 | 0.65 | CHRM2 (0.35) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL7074672 | 0.64 | MDM2 (0.33) | ALDH1A1SMN1; SMN2CACNA1HOPRK1GAA | |
| SCHEMBL6042593 | 0.62 | SLC6A3 (0.37) | ALDH1A1MAPK1OPRK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |