SCHEMBL872826

SCHEMBL872826

CC(C)CC(=O)OC(C)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.53
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP3 P08254 1/20 0.47
MMP9 P14780 1/20 0.47
MMP13 P45452 1/20 0.47
KDM4E B2RXH2 1/20 0.45
MAPT P10636 1/20 0.45
TSHR P16473 1/20 0.44
LPAR1 Q92633 1/20 0.43
FFAR1 O14842 1/20 0.43
LTB4R Q15722 1/20 0.41
LTB4R2 Q9NPC1 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GLA P06280 1/20 0.40
OPRM1 P35372 3/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30688108 0.87 LTB4R (0.54) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL9582353 0.87 HCAR2 (0.51) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL27531115 0.85 CRHBP (0.50) HCAR2MMP1MMP2MMP3MMP9
SCHEMBL3883004 0.85 HCAR2 (0.56) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL11461421 0.85 HCAR2 (0.56) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL16673205 0.84 HCAR2 (0.49) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL27701745 0.83 HCAR2 (0.54) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL27774184 0.83 HCAR2 (0.54) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL9231000 0.83 HCAR2 (0.54) HCAR2KDM4EMAPTTSHRLPAR1
SCHEMBL538486 0.83 HCAR2 (0.54) HCAR2KDM4EMAPTTSHRLPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 487 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 US claimed
EP-4444108-B1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-09-10 EP claimed
EP-4565194-A1 ODOR AND COLORANT STABILIZED COMPOSITIONS Symrise AG (DE) 2025-06-11 EP claimed
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US claimed
WO-2025026525-A1 HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS SYMRISE AG (DE) 2025-02-06 WO claimed
US-20250040580-A1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-02-06 US claimed
EP-3689324-B1 NEW COOLING AGENTS AND PREPARATIONS COMPRISING THEM SYMRISE AG (DE) 2024-11-20 EP claimed
EP-4444108-A1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT Symrise AG (DE) 2024-10-16 EP claimed
US-20240245085-A1 FLAVORING COMPOSITIONS FOR TASTE IMPROVEMENT SYMRISE AG (DE) 2024-07-25 US claimed
US-20240148039-A1 FLAVOURING COMPOSITION WITH BALANCED TASTE PROFILE SYMRISE AG (DE) 2024-05-09 US claimed
CN-102634414-A Preparation method of essence for low-grade flue-cured tobacco cigarette ZHONGMEI SU 2012-08-15 CN claimed
CN-102628229-A Anti-precipitant and its preparation method ZHEJIANG ANOKY AUX Y CO LTD 2012-08-08 CN claimed
CN-102204717-A Formula of mint fragrant tobacco additive essence GUANGZHOU AOJIAN FENGZE BIOLOG TECHNOLOGY CO LTD 2011-10-05 CN claimed
CN-101386724-A Application of vegetable oil, ink compound and high boiling point solvent water-scraped without set-off intaglio ink composition GUANBAO FAN (CN) 2009-03-18 CN claimed
US-20060166857-A1 4,8-Dimethyl-7-nonen-2-one and 4,8-dimethylnonan-2-one used as perfumes SYMRISE GMBH & CO. KG (DE) 2006-07-27 US claimed
CN-1572335-A Self-Service respiratory vaccination instrument for SARS infectious disease CONG FANZI (CN) 2005-02-02 CN claimed
CN-1520846-A Quick-effective aerosol with plant aroma and its preparation 丛繁滋 2004-08-18 CN claimed
CN-1500477-A Quick result aerosol with plant aroma and its preparation 丛繁滋 2004-06-02 CN claimed
CN-1475204-A Medicinal Composition, dry powder vapor, nebula, nebula auxiliary preparation for use through mouth and nose and its preparation method 丛繁滋 2004-02-18 CN claimed
CN-1226589-A Preparation of mono-component anaerobic adhesive for fastening screws and sealing flat surfaces LIANG YIXUN (CN) 1999-08-25 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12568998-B2 Flavouring composition with balanced taste profile TAS2R20, TAS2R50, TAS2R40 HCAR2 848/4885MMP1 4725/4885MMP2 4559/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 HCAR2 3751/4885MMP1 4393/4885MMP2 4728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.