Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565339 | 0.91 | THRA (0.31) | THRATHRBMEN1KMT2A | |
| SCHEMBL7561074 | 0.69 | — | — | |
| SCHEMBL3273265 | 0.60 | TSHR (0.31) | THRATHRB | |
| SCHEMBL9639306 | 0.59 | TSHR (0.35) | THRATHRBMEN1KMT2A | |
| Hexane SCHEMBL28463656 | 0.57 | TSHR (0.58) | THRB | |
| SCHEMBL216962 | 0.56 | ACHE (0.38) | — | |
| SCHEMBL9311279 | 0.54 | THRB (0.56) | THRATHRBMEN1KMT2A | |
| Hexane SCHEMBL8891406 | 0.54 | TSHR (0.61) | THRBMEN1KMT2A | |
| Hexane SCHEMBL27466802 | 0.54 | — | — | |
| Octane SCHEMBL11684722 | 0.52 | TSHR (0.67) | THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659756-B1 | Metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2002-04-03 | — | — | EP | disclosed |
| US-5741868-A | Olefin polymerization process by using a substituted indenyl containing metallocene catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| US-5543373-A | OLEFIN POLYMERIZATION CATALYST | HOECHST AG (DE) | 1996-08-06 | — | — | US | disclosed |
| CN-1109061-A | Metallocenic compound | HOECHST AG (DE) | 1995-09-27 | — | — | CN | disclosed |
| EP-0659756-A1 | Metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-28 | — | — | EP | disclosed |