Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 9/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560777 | 1.00 | RAB9A (0.45) | RAB9ANPC1MAPTKDM4EJUN | |
| SCHEMBL7560426 | 0.89 | BACE1 (0.45) | RAB9ANPC1MAPTKDM4ECYP1A2 | |
| SCHEMBL7560422 | 0.89 | BACE1 (0.45) | RAB9ANPC1MAPTKDM4ECYP1A2 | |
| SCHEMBL7558259 | 0.74 | ABCB1 (0.34) | L3MBTL1 | |
| SCHEMBL7558251 | 0.74 | ABCB1 (0.34) | L3MBTL1 | |
| SCHEMBL7565968 | 0.73 | MAPT (0.40) | RAB9ANPC1MAPTKDM4ECYP1A2 | |
| SCHEMBL7560623 | 0.73 | MAPT (0.40) | RAB9ANPC1MAPTKDM4ECYP1A2 | |
| SCHEMBL7565979 | 0.73 | MAPT (0.40) | RAB9ANPC1MAPTKDM4ECYP1A2 | |
| SCHEMBL7560610 | 0.73 | MAPT (0.40) | RAB9ANPC1MAPTKDM4ECYP1A2 | |
| SCHEMBL8668533 | 0.73 | CHRNB2 (0.41) | RAB9ANPC1MAPTKDM4EJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705837-B1 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5744604-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| US-5677455-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0705837-A2 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1996-04-10 | — | — | EP | disclosed |