Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560767 | 0.73 | RAB9A (0.45) | TBXAS1KDM4ENPC1RAB9AJUN | |
| SCHEMBL7560777 | 0.73 | RAB9A (0.45) | TBXAS1KDM4ENPC1RAB9AJUN | |
| SCHEMBL18123727 | 0.73 | CHRNB2 (0.45) | CHRNB2CHRNA4TBXAS1KDM4ENPC1 | |
| SCHEMBL18110416 | 0.73 | CHRNB2 (0.50) | CHRNB2CHRNA4TBXAS1KDM4ENPC1 | |
| SCHEMBL8527896 | 0.70 | CHRNB2 (0.42) | CHRNB2CHRNA4TBXAS1CYP11B1CYP11B2 | |
| Bicarbonate SCHEMBL9520380 | 0.69 | CHRNB2 (0.62) | CHRNB2CHRNA4TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL8527898 | 0.69 | TBXAS1 (0.39) | CHRNB2CHRNA4TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL9826871 | 0.69 | TBXAS1 (0.53) | CHRNB2CHRNA4TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL9826864 | 0.69 | TBXAS1 (0.53) | CHRNB2CHRNA4TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL9843049 | 0.68 | TBXAS1 (0.47) | CHRNB2CHRNA4TBXAS1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849766-A | Carbamoyl substituted heterocycles | ELI LILLY AND COMPANY (US) | 1998-12-15 | — | — | US | disclosed |