⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565339 | 0.81 | THRA (0.31) | — | |
| SCHEMBL7557682 | 0.63 | — | — | |
| SCHEMBL7646408 | 0.58 | — | — | |
| SCHEMBL7647494 | 0.57 | — | — | |
| SCHEMBL8753094 | 0.57 | NR1H4 (0.31) | — | |
| SCHEMBL8951774 | 0.56 | HTR6 (0.38) | — | |
| SCHEMBL4654239 | 0.54 | — | — | |
| SCHEMBL9624196 | 0.53 | PTGS1 (0.35) | — | |
| SCHEMBL22384680 | 0.52 | XDH (0.34) | — | |
| SCHEMBL14715750 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659756-B1 | Metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2002-04-03 | — | — | EP | disclosed |
| US-5741868-A | Olefin polymerization process by using a substituted indenyl containing metallocene catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| US-5543373-A | OLEFIN POLYMERIZATION CATALYST | HOECHST AG (DE) | 1996-08-06 | — | — | US | disclosed |
| CN-1109061-A | Metallocenic compound | HOECHST AG (DE) | 1995-09-27 | — | — | CN | disclosed |
| EP-0659756-A1 | Metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-28 | — | — | EP | disclosed |