Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9355090 | 0.84 | TDP1 (0.88) | KMT2ATDP1MEN1ALDH1A1MAPT | |
| SCHEMBL23855 | 0.84 | TDP1 (1.00) | KMT2ATDP1MEN1ALDH1A1MAPT | |
| SCHEMBL29349835 | 0.84 | TDP1 (1.00) | KMT2ATDP1MEN1ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL7560884 | 0.83 | KMT2A (0.67) | KMT2ATDP1MEN1ALDH1A1PKM | |
| Sulfuric Acid SCHEMBL22406114 | 0.81 | KMT2A (0.64) | KMT2ATDP1MEN1ALDH1A1PKM | |
| SCHEMBL8745318 | 0.81 | TDP1 (0.93) | KMT2ATDP1MEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL874057 | 0.81 | TDP1 (0.93) | KMT2ATDP1MEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL504482 | 0.81 | TDP1 (0.93) | KMT2ATDP1MEN1ALDH1A1MAPT | |
| Methane SCHEMBL1599658 | 0.81 | TDP1 (0.93) | KMT2ATDP1MEN1ALDH1A1MAPT | |
| Water SCHEMBL3137651 | 0.81 | TDP1 (0.93) | KMT2ATDP1MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020169151-A1 | Inhibition of vascular smooth muscle cell proliferation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-14 | — | — | US | disclosed |
| US-6440954-B1 | Inhibition of vascular smooth muscle cell proliferation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-08-27 | — | — | US | disclosed |