Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669788 | 0.83 | SCN9A (0.40) | SCN9AEGFRSRCALDH1A1KDM4E | |
| SCHEMBL13971702 | 0.82 | MAPT (0.51) | ALDH1A1KDM4EMAPTGAACASP1 | |
| SCHEMBL471925 | 0.79 | KDM4E (0.55) | SCN9AEGFRSRCALDH1A1KDM4E | |
| SCHEMBL6295317 | 0.79 | KDM4E (0.55) | SCN9AEGFRSRCALDH1A1KDM4E | |
| SCHEMBL497627 | 0.79 | KDM4E (0.55) | SCN9AEGFRSRCALDH1A1KDM4E | |
| SCHEMBL29415605 | 0.79 | KDM4E (0.55) | SCN9AEGFRSRCALDH1A1KDM4E | |
| Water SCHEMBL29189815 | 0.78 | KDM4E (0.54) | SCN9AEGFRSRCALDH1A1KDM4E | |
| SCHEMBL10372737 | 0.77 | MTNR1A (0.49) | SCN9AEGFRSRCALDH1A1KDM4E | |
| SCHEMBL5460837 | 0.76 | ALDH1A1 (0.44) | EGFRALDH1A1KDM4EMAPTGAA | |
| Sulfurous Acid SCHEMBL28577186 | 0.74 | MAPT (0.50) | SCN9AEGFRSRCALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0744955-B1 | CYCLIC HEPTAPEPTIDE ANTI-INFLAMMATORY AGENT | UNIV CALIFORNIA (US) | 2002-07-31 | — | — | EP | disclosed |
| US-5593960-A | PRODUCING CYCLOMARIN A FROM FERMENTATION OF STREPTOMYCES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-01-14 | — | — | US | disclosed |
| US-5444043-A | Cyclic depsipeptide non-steroidal antiinflammatory agent | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-08-22 | — | — | US | disclosed |