Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 4/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497627 | 1.00 | KDM4E (0.55) | KDM4EMAPTLMNATSHRBLM | |
| SCHEMBL29415605 | 1.00 | KDM4E (0.55) | KDM4EMAPTLMNATSHRBLM | |
| SCHEMBL6295317 | 1.00 | KDM4E (0.55) | KDM4EMAPTLMNATSHRBLM | |
| Water SCHEMBL29189815 | 0.98 | KDM4E (0.54) | KDM4EMAPTLMNATSHRBLM | |
| Sulfurous Acid SCHEMBL28577186 | 0.94 | MAPT (0.50) | KDM4EMAPTLMNATSHRBLM | |
| Tryptophan SCHEMBL2721525 | 0.89 | KMT2A (0.76) | KDM4EMAPTLMNATSHRBLM | |
| SCHEMBL27795130 | 0.88 | SLC1A1 (0.55) | KDM4EMAPTLMNATSHRBLM | |
| SCHEMBL2263891 | 0.85 | KDM4E (0.55) | KDM4EMAPTLMNATSHRBLM | |
| SCHEMBL7694812 | 0.85 | KDM4E (0.55) | KDM4EMAPTLMNATSHRBLM | |
| SCHEMBL7694420 | 0.84 | KDM4E (0.54) | KDM4EMAPTLMNATSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1878 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026099341-A1 | BIOCONTAINMENT OF UNWANTED ENGINEERED CELLS USING NON-NATURAL AMINO ACIDS | SNIPR BIOME APS (DK) | 2026-05-15 | — | — | WO | claimed |
| CN-122017244-A | Plasma metabolism marker for kidney cancer diagnosis and application thereof | 哈尔滨脉图精准技术有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-14 | — | — | US | claimed |
| US-12533325-B2 | Composition and method for preventing or treating opioid withdrawal symptoms | ANDRY JONATHAN B (US) | 2026-01-27 | — | — | US | claimed |
| US-12415834-B2 | GhR-binding peptide and composition comprising same | PEPTIDREAM INC. (JP) | 2025-09-16 | — | — | US | claimed |
| US-20250246314-A1 | METHODS FOR THE DETECTION AND TREATMENT OF PANCREATIC DUCTAL ADENOCARCINOMA | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2025-07-31 | — | — | US | claimed |
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2025-07-08 | — | — | US | claimed |
| US-12329726-B2 | Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-06-17 | — | — | US | claimed |
| CN-119736177-A | Yeast engineering strain for synthesizing melatonin and construction method and application thereof | 河南牧业经济学院 | 2025-04-01 | — | — | CN | claimed |
| WO-2025016307-A1 | HEALTH HOMEOSTASIS MODEL, ELASTIC HOMEOSTASIS MODEL, AND USAGE METHOD THEREFOR | 汤臣倍健股份有限公司 | 2025-01-23 | — | — | WO | claimed |
| US-20030113882-A1 | Methods for the preparation of beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-06-19 | — | — | US | claimed |
| EP-0759299-B1 | Potentiation of serotonin response | LILLY CO ELI (US) | 2000-04-26 | — | — | EP | claimed |
| US-5958429-A | TREATING DEPRESSION | ELI LILLY AND COMPANY (US) | 1999-09-28 | — | — | US | claimed |
| WO-1997006792-A1 | POTENTIATION OF SEROTONIN RESPONSE | ELI LILLY AND COMPANY (US) | 1997-02-27 | — | — | WO | claimed |
| EP-0759299-A1 | Potentiation of serotonin response | ELI LILLY AND COMPANY (US) | 1997-02-26 | — | — | EP | claimed |
| US-5081225-A | Novel antibiotic, janthinocin | E. R. SQUIBB & SONS, INC. (US) | 1992-01-14 | — | — | US | claimed |
| EP-0234186-B1 | USE OF OLIGOPEPTIDS FOR THE TREATMENT OF CEREBRAL DISORDERS | Fresenius AG (DE) | 1991-11-06 | — | — | EP | claimed |
| EP-0234186-A1 | Use of oligopeptids for the treatment of cerebral disorders | Fresenius AG (DE) | 1987-09-02 | — | — | EP | claimed |
| EP-0058111-B1 | 5-ACETYLOXY-L-TRYPTOPHANE AND ITS SALTS, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USES | Laboratoires Merck-Clévenot (FR) | 1985-10-23 | — | — | EP | claimed |
| US-4283337-A | Process for the purification of tryptophane and derivatives of tryptophane | DEUTSCHE GOLD UND- SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-08-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | DNPEP, NPEPPS, PAM | KDM4E 3819/4885MAPT 1350/4885LMNA 4762/4885 |
| US-12415834-B2 | GhR-binding peptide and composition comprising same | GHRHR, GHSR, GIPR | KDM4E 4589/4885MAPT 4092/4885LMNA 4434/4885 |
| US-12533325-B2 | Composition and method for preventing or treating opioid withdrawal symptoms | S100B, SLC6A12, SLC6A13 | KDM4E 2175/4885MAPT 302/4885LMNA 3102/4885 |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | MET, THRB, ABAT | KDM4E 2649/4885MAPT 1679/4885LMNA 4184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.