Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CTSE | P14091 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475849 | 0.75 | BACE1 (0.37) | MMEACEMMP2MMP9BACE1 | |
| SCHEMBL9101106 | 0.75 | ACE (0.37) | MMEACEMMP2MMP9BACE1 | |
| SCHEMBL7534852 | 0.74 | MME (0.47) | MMEACEMMP2LTA4HMMP1 | |
| SCHEMBL8652349 | 0.71 | LTA4H (0.43) | MMEACEMMP2LTA4HMMP1 | |
| SCHEMBL8129676 | 0.70 | ACACB (0.38) | BACE1CTSDCTSE | |
| SCHEMBL9069940 | 0.68 | CTSK (0.34) | BACE1CTSDCTSE | |
| SCHEMBL8708285 | 0.66 | MAPT (0.30) | — | |
| Xenortide A SCHEMBL29886039 | 0.62 | ANPEP (0.52) | MMP2MMP9MMP3 | |
| SCHEMBL17992991 | 0.62 | MMP1 (0.50) | ACEMMP2MMP9MMP1MMP3 | |
| SCHEMBL17992833 | 0.62 | MMP1 (0.50) | ACEMMP2MMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192142-A1 | CYCLO-IMINO DEPSIPEPTIDES AND THEIR UTILIZATION IN CONTROLLING ENDOPARASITES | Bayer Aktiengesellschaft (DE) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076985-A1 | CYCLO-IMINO DEPSIPEPTIDES AND THEIR UTILIZATION IN CONTROLLING ENDOPARASITES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-21 | — | — | WO | disclosed |