SCHEMBL7561301

SCHEMBL7561301

CCCCCc1ccccc1-c1cccc2[nH]nnc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
PTGS2 P35354 2/20 0.35
ALOX5 P09917 1/20 0.35
KCNH2 Q12809 1/20 0.35
HSD11B1 P28845 1/20 0.34
BID P55957 3/20 0.34
MCL1 Q07820 3/20 0.34
BCL2L1 Q07817 2/20 0.34
BAK1 Q16611 2/20 0.34
KAT8 Q9H7Z6 2/20 0.34
TLR8 Q9NR97 1/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
EP300 Q09472 1/20 0.34
KAT2A Q92830 1/20 0.34
KAT2B Q92831 1/20 0.34
KAT5 Q92993 1/20 0.34
SAE1 Q9UBE0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4639413 0.99 LIPG (0.41) NR1H2NR1H3LIPGPTGS2KCNH2
SCHEMBL29565391 0.99 LIPG (0.41) NR1H2NR1H3LIPGPTGS2KCNH2
SCHEMBL29538435 0.96 NR1H2 (0.34) NR1H2NR1H3LIPGTLR8
SCHEMBL29565133 0.88 ALOX5 (0.45) LIPGPTGS2ALOX5BIDMCL1
SCHEMBL9068079 0.87 ALOX5 (0.44) NR1H2NR1H3LIPGPTGS2ALOX5
SCHEMBL29466095 0.87 LIPG (0.40) LIPGPTGS2ALOX5KCNH2BID
SCHEMBL299944 0.87 LIPG (0.40) LIPGPTGS2ALOX5KCNH2BID
SCHEMBL5416743 0.86 KDM4E (0.34)
SCHEMBL8633987 0.85 LIPG (0.42) LIPGPTGS2ALOX5KCNH2BID
SCHEMBL460020 0.85 LIPG (0.42) LIPGPTGS2ALOX5KCNH2BID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1228174-A1 AQUEOUS FABRIC SOFTENER COMPOSITIONS CONTAINING HIGHLY UNSATURATED ACTIVE AND SUBSTANTIVE CHELANT THE PROCTER & GAMBLE COMPANY (US) 2002-08-07 EP disclosed
WO-2001034743-A1 AQUEOUS FABRIC SOFTENER COMPOSITIONS CONTAINING HIGHLY UNSATURATED ACTIVE AND CHELANT THE PROCTER & GAMBLE COMPANY (US) 2001-05-17 WO disclosed