Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IL18 | Q14116 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23754112 | 0.79 | PPARG (0.45) | PPARAPPARDMAPTKDM4EMEN1 | |
| SCHEMBL4700424 | 0.78 | PPARA (0.64) | PPARAPPARDMAPTALDH1A1KDM4E | |
| SCHEMBL11763480 | 0.78 | PPARG (0.44) | PPARAPPARDMAPTKDM4EMEN1 | |
| SCHEMBL2554944 | 0.77 | MAPT (0.50) | PPARAMAPTALDH1A1RAB9ALMNA | |
| SCHEMBL11540230 | 0.75 | ALDH1A1 (0.44) | PPARAMAPTALDH1A1PARP10LMNA | |
| SCHEMBL21698056 | 0.75 | ALDH1A1 (0.48) | PPARAPPARDMAPTALDH1A1MMP2 | |
| SCHEMBL20594081 | 0.75 | MMP2 (0.45) | PPARAPPARDMAPTALDH1A1MMP2 | |
| SCHEMBL22349709 | 0.74 | CYP2A6 (0.45) | PPARAPPARDMAPTALDH1A1MGLL | |
| SCHEMBL4692295 | 0.72 | PPARA (0.66) | PPARAPPARDMAPTALDH1A1MGLL | |
| SCHEMBL11067259 | 0.72 | OPRK1 (0.59) | PPARAPPARDMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937063-B1 | ARYLOXYPROPANOLAMINE DERIVATIVES, METHOD OF PREPARATION AND APPLICATIONS THEREOF | VIRBAC SA (FR) | 2002-04-10 | — | — | EP | disclosed |
| EP-0937063-A1 | ARYLOXYPROPANOLAMINE DERIVATIVES, METHOD OF PREPARATION AND APPLICATIONS THEREOF | VIRBAC S.A. (FR) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998020005-A1 | ARYLOXYPROPANOLAMINE DERIVATIVES, METHOD OF PREPARATION AND APPLICATIONS THEREOF | VIRBAC S.A. (FR) | 1998-05-14 | — | — | WO | disclosed |