SCHEMBL7561569

SCHEMBL7561569

CNC(CN)CCN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29180432 0.88
SCHEMBL31661413 0.82 OPRD1 (0.33)
SCHEMBL20435078 0.81 NFKB1 (0.35)
SCHEMBL708860 0.81
SCHEMBL199578 0.80
SCHEMBL19443305 0.80
SCHEMBL25019126 0.78
SCHEMBL16391068 0.78
SCHEMBL6027874 0.78
SCHEMBL14002730 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210330600-A1 NANOPARTICLE COMPOSITIONS FOR EFFICIENT NUCLEIC ACID DELIVERY AND METHODS OF MAKING AND USING THE SAME TIBA BIOTECH LLC (US) 2021-10-28 US claimed
EP-3898942-A1 NANOPARTICLE COMPOSITIONS FOR EFFICIENT NUCLEIC ACID DELIVERY AND METHODS OF MAKING AND USING THE SAME Tiba Biotech LLC (US) 2021-10-27 EP claimed
WO-2020132196-A1 NANOPARTICLE COMPOSITIONS FOR EFFICIENT NUCLEIC ACID DELIVERY AND METHODS OF MAKING AND USING THE SAME TIBA BIOTECH LLC (US) 2020-06-25 WO claimed
CN-111620870-B Compound and application thereof in expansion of hematopoietic stem cells and/or hematopoietic progenitor cells 蒙特利尔大学 2023-01-03 CN disclosed
EP-3440076-B1 HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS GLAXOSMITHKLINE IP DEV LTD (GB) 2022-06-01 EP disclosed
US-20220153751-A1 BIFUNCTIONAL COMPOUNDS BIOTHERYX, INC. (US) 2022-05-19 US disclosed
US-20210330600-A1 NANOPARTICLE COMPOSITIONS FOR EFFICIENT NUCLEIC ACID DELIVERY AND METHODS OF MAKING AND USING THE SAME TIBA BIOTECH LLC (US) 2021-10-28 US disclosed
US-20210238172-A1 HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS AND METHODS OF USING THE SAME GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2021-08-05 US disclosed
EP-3508620-B1 UREYLENE ADDITIVE, ITS USE AND A PREPARATION METHOD THEREFOR ATOTECH DEUTSCHLAND GMBH (DE) 2021-05-19 EP disclosed
US-20210113712-A1 METHODS FOR PREPARING CELL TARGETING CONJUGATES AND CONJUGATES OBTAINABLE BY SAID METHODS LINXIS B V (NL) 2021-04-22 US disclosed
US-20200345862-A1 TRANSITION METAL-BASED FUNCTIONAL MOIETIES FOR PREPARING CELL TARGETING CONJUGATES LINXIS B V (NL) 2020-11-05 US disclosed
US-10647718-B2 Compounds and use thereof in the expansion of hematopoietic stem cells and/or hematopoietic progenitor cells Universitéde Montréal (CA) 2020-05-12 US disclosed
EP-3134409-B1 COMPOUNDS AND USE THEREOF IN THE EXPANSION OF HEMATOPOIETIC STEM CELLS AND/OR HEMATOPOIETIC PROGENITOR CELLS UNIV MONTREAL (CA) 2020-02-12 EP disclosed
EP-3508620-A1 UREYLENE ADDITIVE, ITS USE AND A PREPARATION METHOD THEREFOR ATOTECH Deutschland GmbH (DE) 2019-07-10 EP disclosed
WO-2019069269-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) USEFUL IN TREATING HIV GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-04-11 WO disclosed
US-20170037047-A1 COMPOUNDS AND USE THEREOF IN THE EXPANSION OF HEMATOPOIETIC STEM CELLS AND/OR HEMATOPOIETIC PROGENITOR CELLS UNIVERSITE DE MONTREAL (CA) 2017-02-09 US disclosed
WO-2016196393-A2 AUTOPHAGY-INHIBITING COMPOUNDS AND USES THEREOF PRESAGE BIOSCIENCES, INC. (US) 2016-12-08 WO disclosed
US-20160257699-A1 BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS FORMA THERAPEUTICS, INC. 2016-09-08 US disclosed
WO-2002057372-A2 STABILIZATION OF VINYLETHER AND VINYL LACTAM FORMULATIONS AGAINST HYDROLYSIS ISP INVESTMENTS INC. (US) 2002-07-25 WO disclosed
US-6417356-B1 MIXTURE WITH AMINE OR POLYAMINE; CURING AGENTS; STORAGE STABILITY ISP INVESTMENTS INC. 2002-07-09 US disclosed