Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 16/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058802 | 0.81 | TSHR (0.41) | C3AR1TSHRRAB9AMMP1MMP3 | |
| SCHEMBL7345274 | 0.73 | CHRM3 (0.34) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL7346487 | 0.70 | MMP13 (0.38) | TSHRMMP1MMP3MMP7MMP9 | |
| SCHEMBL7346041 | 0.67 | HTT (0.38) | TSHRMMP1MMP3MMP7MMP9 | |
| SCHEMBL7377055 | 0.67 | ALDH1A1 (0.38) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL7053159 | 0.66 | MMP13 (0.36) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL2274463 | 0.66 | C3AR1 (0.43) | C3AR1 | |
| SCHEMBL1024986 | 0.66 | C3AR1 (0.43) | C3AR1 | |
| SCHEMBL7059787 | 0.65 | NAMPT (0.40) | C3AR1TSHRMMP1MMP3MMP7 | |
| SCHEMBL7346270 | 0.65 | ALDH1A1 (0.43) | TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948489-A1 | PIPERAZINE COMPOUNDS AS INHIBITORS OF MMP OR TNF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998027069-A1 | PIPERAZINE COMPOUNDS AS INHIBITORS OF MMP OR TNF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-25 | — | — | WO | disclosed |