SCHEMBL756163

SCHEMBL756163

O=[PH](OCc1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 4/20 0.45
IDO1 P14902 1/20 0.43
AGXT P21549 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A3 Q01959 2/20 0.39
RAB9A P51151 2/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALPG P10696 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36370 0.79 TSHR (0.52) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL29806030 0.79 TSHR (0.52) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL969878 0.78 TSHR (0.46) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL27454336 0.78 MAPT (0.49) ALDH1A1CA1CA2CA9RAB9A
SCHEMBL21121801 0.77 TSHR (0.50) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL313072 0.76 NPSR1 (0.35) TSHRALDH1A1L3MBTL1KMT2AGAA
SCHEMBL7054240 0.76 TSHR (0.48) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL28000592 0.76 ALDH1A1 (0.33) ALDH1A1RAB9AMAPK1KMT2AHIF1A
SCHEMBL9857401 0.76 ALDH1A1 (0.33) TSHRALDH1A1IDO1MAPK1KMT2A
SCHEMBL11025852 0.76 TAAR1 (0.36) IDO1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1238423-C Thermoplastic resin composition and molded object thereof POLYPLASTICS CO (JP) 2006-01-25 CN claimed
EP-0082057-B1 PROCESS FOR PREPARING PHOSPHINAMIDES, APPLICATIONS AND PRODUCTS SOCIETE NATIONALE ELF AQUITAINE (FR) 1986-04-30 EP claimed
EP-0082057-A2 Process for preparing phosphinamides, applications and products SOCIETE NATIONALE ELF AQUITAINE (FR) 1983-06-22 EP claimed
CN-112898738-A Epoxy resin composition, prepreg, laminate, printed wiring board, and cured product using same 日铁化学材料株式会社 2021-06-04 CN disclosed
CN-112585189-A Phosphorus-containing epoxy resin, epoxy resin composition, prepreg, laminate, material for circuit board, and cured product 日铁化学材料株式会社 2021-03-30 CN disclosed
EP-2758059-A1 SUBSTITUTED PYRIMIDINES Merck Sharp & Dohme Corp. (US) 2014-07-30 EP disclosed
CN-101970733-B Polyethylene naphthalate fiber and method for producing same TEIJIN FIBERS LTD 2014-02-05 CN disclosed
CN-101970734-B Polyethylene naphthalate fiber and process for producing polyethylene naphthalate fiber TEIJIN FIBERS LTD 2014-02-05 CN disclosed
US-8476372-B2 Polyester fiber and method for its production, and tire cord, tire, belt-reinforcing fiber material and belt comprising the polyester fiber TEIJIN FIBERS LIMITED (JP) 2013-07-02 US disclosed
WO-2013043624-A1 SUBSTITUTED PYRIMIDINES MERCK SHARP & DOHME CORP. (US) 2013-03-28 WO disclosed
CN-101946032-B Polyester fiber, process for producing the polyester fiber, and tire code, tire, fiber material for reinforcing belt and belt each comprising the polyester fiber TEIJIN FIBERS LTD 2013-03-20 CN disclosed
EP-2261403-A1 POLYESTER FIBER, PROCESS FOR PRODUCING THE POLYESTER FIBER, AND TIRE CODE, TIRE, FIBER MATERIAL FOR REINFORCING BELT AND BELT EACH COMPRISING THE POLYESTER FIBER Teijin Fibers Limited (JP) 2010-12-15 EP disclosed
EP-2258891-A1 POLYETHYLENE NAPHTHALATE FIBER AND PROCESS FOR PRODUCING THE POLYETHYLENE NAPHTHALATE FIBER Teijin Fibers Limited (JP) 2010-12-08 EP disclosed
EP-2253747-A1 POLYETHYLENE NAPHTHALATE FIBER AND PROCESS FOR PRODUCING THE POLYETHYLENE NAPHTHALATE FIBER Teijin Fibers Limited (JP) 2010-11-24 EP disclosed
US-20090163444-A1 PHOSPHO-INDOLES AS HIV INHIBITORS IDENIX PHARMACEUTICALS LLC 2009-06-25 US disclosed
US-7534809-B2 Phospho-indoles as HIV inhibitors IDENIX PHARMACEUTICALS, INC. (US) 2009-05-19 US disclosed
CN-101384669-A Thermoplastic resin composition and liquid crystal display part or information recording medium part using the composition POLYPLASTICS CO (JP) 2009-03-11 CN disclosed
CN-1828383-A Liquid crystal display component POLYPLASTICS CO (JP) 2006-09-06 CN disclosed
CN-1238423-C Thermoplastic resin composition and molded object thereof POLYPLASTICS CO (JP) 2006-01-25 CN disclosed
CN-1361810-A Thermoplastic resin composition and molded object thereof POLYPLASTICS CO (JP) 2002-07-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090163444-A1 PHOSPHO-INDOLES AS HIV INHIBITORS IDO1, PPP5C, INMT TSHR 4573/4885ALDH1A1 4061/4885IDO1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.