Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422283 | 0.91 | KDM4E (0.48) | KDM4EALDH1A1KMT2ANFKB1CYP1A2 | |
| SCHEMBL7428454 | 0.90 | KDM4E (0.47) | KDM4EALDH1A1KMT2ANFKB1CYP1A2 | |
| SCHEMBL7701525 | 0.80 | GNG2 (0.52) | KDM4EALDH1A1KMT2ANFKB1CYP1A2 | |
| SCHEMBL10187519 | 0.80 | CYP1A2 (0.40) | KDM4EALDH1A1KMT2ANFKB1CYP1A2 | |
| SCHEMBL7427640 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1KMT2ANFKB1CYP1A2 | |
| SCHEMBL7427638 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1KMT2ANFKB1CYP1A2 | |
| SCHEMBL10187517 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1KMT2ANFKB1CYP1A2 | |
| SCHEMBL7478838 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1KMT2ANFKB1CYP1A2 | |
| SCHEMBL7478843 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1KMT2ANFKB1CYP1A2 | |
| SCHEMBL7697841 | 0.73 | KDM4E (0.39) | KDM4EALDH1A1KMT2ANFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006560-A1 | TRICYCLIC HETEROAROMATICS AND THEIR DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |