Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431009 | 0.86 | NFKB1 (0.41) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL7488775 | 0.85 | NFKB1 (0.41) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL7429305 | 0.85 | NFKB1 (0.41) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL7426587 | 0.85 | NFKB1 (0.41) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL7429273 | 0.84 | MMP1 (0.41) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL7427294 | 0.84 | KMO (0.41) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL7424384 | 0.84 | KMO (0.41) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL7431796 | 0.83 | NFKB1 (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL7430672 | 0.83 | MMP1 (0.41) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL7424360 | 0.83 | MMP1 (0.41) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350885-B1 | TREATMENT OF MULTIPLE SCLEROSIS, ATHEROSCLEROTIC PLAQUE RUPTURE, AORTIC ANEURYSM, HEART FAILURE, LEFT VENTRICULAR DILATION, RESTENOSIS, PERIODONTAL DISEASE, CORNEAL ULCERATION, TREATMENT OF BURNS, DECUBITAL ULCERS, WOUND HEALING AGENT | WARNER-LAMBERT COMPANY | 2002-02-26 | — | — | US | disclosed |