Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562178 | 0.98 | THRA (0.43) | THRATHRBSIGMAR1SPHK2SPHK1 | |
| SCHEMBL7561616 | 0.98 | THRA (0.43) | THRATHRBSIGMAR1SPHK2SPHK1 | |
| SCHEMBL8076543 | 0.98 | THRA (0.43) | THRATHRBSIGMAR1SPHK2SPHK1 | |
| SCHEMBL8070936 | 0.98 | THRA (0.43) | THRATHRBSIGMAR1SPHK2SPHK1 | |
| SCHEMBL8076082 | 0.98 | THRA (0.43) | THRATHRBSIGMAR1SPHK2SPHK1 | |
| SCHEMBL7560868 | 0.98 | THRA (0.43) | THRATHRBSIGMAR1SPHK2SPHK1 | |
| SCHEMBL7560719 | 0.93 | SIGMAR1 (0.40) | SIGMAR1SPHK2SPHK1CYP3A4IDO1 | |
| SCHEMBL2177163 | 0.87 | THRA (0.47) | THRATHRBCYP3A4TDP1MAOB | |
| SCHEMBL6679345 | 0.87 | TDP1 (0.40) | THRATHRBSPHK2SPHK1CYP3A4 | |
| SCHEMBL9673266 | 0.85 | THRA (0.50) | THRATHRBSIGMAR1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637580-B1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |