SCHEMBL7562012

SCHEMBL7562012

CCCOC(Cl)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
SCN1A P35498 3/20 0.44
SCN2A Q99250 3/20 0.44
SCN3A Q9NY46 3/20 0.44
HTR2A P28223 2/20 0.44
HRH1 P35367 2/20 0.44
TSHR P16473 2/20 0.44
HTT P42858 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
ADRA2A P08913 1/20 0.44
CHRM1 P11229 1/20 0.44
ADRA2B P18089 1/20 0.44
CHRM3 P20309 1/20 0.44
SLC6A2 P23975 1/20 0.44
HRH2 P25021 1/20 0.44
HTR2C P28335 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6427368 0.88 LTA4H (0.44) LMNASCN1ASCN2ASCN3AHTR2A
SCHEMBL27546960 0.86 LTA4H (0.44) LMNASCN1ASCN2ASCN3AHTR2A
SCHEMBL5805895 0.85 NPC1 (0.44) LMNASCN1ASCN2ASCN3AHTR2A
SCHEMBL28646240 0.85 NPC1 (0.44) LMNASCN1ASCN2ASCN3AHTR2A
SCHEMBL27477321 0.85 NPC1 (0.44) LMNASCN1ASCN2ASCN3AHTR2A
SCHEMBL4891068 0.83 HTR2A (0.46) LMNASCN1ASCN2ASCN3AHTR2A
SCHEMBL7570154 0.81 LMNA (0.55) LMNASCN1ASCN2ASCN3AHTR2A
SCHEMBL4384773 0.80 HTT (0.44) LMNASCN1ASCN2ASCN3AHTR2A
SCHEMBL10650273 0.80 HTR2A (0.45) LMNASCN1ASCN2ASCN3AHTR2A
SCHEMBL29277742 0.78 HTT (0.43) LMNASCN1ASCN2ASCN3AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102791667-B Method for producing high purity aromatic methyl alcohol, and high purity aromatic methyl alcohol composition having excellent storage stability UBE INDUSTRIES 2014-11-05 CN disclosed
CN-102791667-A Method for producing high purity aromatic methyl alcohol, and high purity aromatic methyl alcohol composition having excellent storage stability UBE INDUSTRIES 2012-11-21 CN disclosed
CN-1143858-C 6, 9-disubstituted 2- [ trans- (aminocyclohexyl) amino ] purines, compositions and uses thereof ������ҩ�����޹�˾ 2004-03-31 CN disclosed
EP-0637580-B1 Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL CO (JP) 2002-08-14 EP disclosed
US-6063940-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-05-16 US disclosed
US-5637736-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-10 US disclosed
EP-0710235-A4 1996-06-12 EP disclosed
EP-0710235-A1 ENDOTHELIN ANTAGONISTS MERCK & CO. INC. (US) 1996-05-08 EP disclosed
EP-0637580-A1 Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-02-08 EP disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed