SCHEMBL4891068

SCHEMBL4891068

CCOC(Cl)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.46
HRH1 P35367 3/20 0.46
TDP1 Q9NUW8 1/20 0.45
TSHR P16473 2/20 0.44
LMNA P02545 4/20 0.42
SCN1A P35498 3/20 0.42
SCN2A Q99250 3/20 0.42
SCN3A Q9NY46 3/20 0.42
HTT P42858 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP1A2 P05177 1/20 0.42
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM5 P08912 1/20 0.42
ADRA2A P08913 1/20 0.42
CYP2D6 P10635 1/20 0.42
CHRM1 P11229 1/20 0.42
ADRA2B P18089 1/20 0.42
CHRM3 P20309 1/20 0.42
SLC6A2 P23975 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethylamine SCHEMBL7570158 0.90 HTT (0.49) HTR2AHRH1TDP1TSHRLMNA
SCHEMBL7562012 0.83 LMNA (0.44) HTR2AHRH1TDP1TSHRLMNA
SCHEMBL6427368 0.79 LTA4H (0.44) HTR2AHRH1TDP1TSHRLMNA
SCHEMBL11247443 0.79 TSHR (0.46) HTR2AHRH1TDP1TSHRLMNA
SCHEMBL28453256 0.78 HTR2A (0.43) HTR2AHRH1TDP1TSHRLMNA
SCHEMBL27546960 0.78 LTA4H (0.44) HTR2AHRH1TSHRLMNASCN1A
SCHEMBL15277287 0.77 TSHR (0.39) HTR2AHRH1TSHRLMNASCN1A
SCHEMBL2982882 0.77 L3MBTL1 (0.47) TDP1TSHRL3MBTL1CYP1A2CYP2D6
SCHEMBL1470888 0.77 HTR2A (0.42) HTR2AHRH1TDP1TSHRLMNA
SCHEMBL5805895 0.77 NPC1 (0.44) HTR2AHRH1TSHRLMNASCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025233682-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS AND USES THEREOF LIGACHEM BIOSCIENCES INC. (KR) 2025-11-13 WO disclosed
EP-4423069-A1 INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF Arcus Biosciences, Inc. (US) 2024-09-04 EP disclosed
WO-2023077046-A1 INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF ARCUS BIOSCIENCES, INC. (US) 2023-05-04 WO disclosed
US-10633470-B2 Method of producing a conjugated diene polymer, a modified conjugated diene polymer, and a vinyl cis-polybutadiene composition UBE INDUSTRIES, LTD. (JP) 2020-04-28 US disclosed
US-10508163-B2 Conjugated diene polymer and modified conjugated diene polymer produced using the same, rubber composition for tire, and rubber composition for rubber belt UBE INDUSTRIES, LTD. (JP) 2019-12-17 US disclosed
US-20190256628-A1 Method of Producing a Conjugated Diene Polymer, a Modified Conjugated Diene Polymer, and a Vinyl Cis-Polybutadiene Composition UBE INDUSTRIES, LTD. (JP) 2019-08-22 US disclosed
US-10053526-B2 Catalyst for conjugated diene polymerization, conjugated diene polymer, modified conjugated diene polymer, polybutadiene, and compositions comprising foregoing UBE INDUSTRIES, LTD. (JP) 2018-08-21 US disclosed
US-20180079844-A1 \"Conjugated Diene Polymer and Modified Conjugated Diene Polymer Produced Using the Same, Rubber Composition for Tire, And Rubber Composition for Rubber Belt\ UBE INDUSTRIES, LTD. (JP) 2018-03-22 US disclosed
EP-2975067-B1 CATALYST FOR USE IN POLYMERIZATION OF CONJUGATED DIENE, CONJUGATED DIENE POLYMER AND MODIFIED CONJUGATED DIENE POLYMER EACH PRODUCED USING SAID CATALYST, METHODS RESPECTIVELY FOR PRODUCING SAID POLYMERS, RUBBER COMPOSITION FOR TIRES, AND RUBBER COMPOSITION FOR RUBBER BELTS UBE INDUSTRIES (JP) 2017-10-04 EP disclosed
US-20170158786-A1 CATALYST FOR CONJUGATED DIENE POLYMERIZATION, CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, POLYBUTADIENE, AND COMPOSITIONS COMPRISING FOREGOING UBE INDUSTRIES, LTD. (JP) 2017-06-08 US disclosed
US-5716710-A FOR TRANSFERRING COLOR IMAGES FROM DONOR TO RECEIVER ELEMENTS BY LAMINATION USING CONTROLLED DRY HEAT AND PRESSURE, THEN PEELING, FOR HIGH RESOLUTION EASTMAN KODAK COMPANY (US) 1998-02-10 US disclosed
US-5705314-A IMAGES AND TRANSFERRING WITH HIGH RESOLUTION EASTMAN KODAK COMPANY (US) 1998-01-06 US disclosed
EP-0789277-A2 Method for preparing prepress color proof and intermediate receiver element and carrier plate useful therein EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1997-08-13 EP disclosed
US-5637736-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-10 US disclosed
US-5633116-A CUSHIONING LAYER PREVENTS MINUS DENSITY DEFECTS; CARRIER PLATE WITH THERMOPLASTIC ADHESIVE EASTMAN KOKAK COMPANY (US) 1997-05-27 US disclosed
WO-1996033190-A1 QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THE RESULTANT INTERMEDIATES, THEIR USE AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL UCLAF (FR) 1996-10-24 WO disclosed
EP-0637580-A1 Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-02-08 EP disclosed
US-4891246-A PREVENTION OF OXIDATION OF BASE METAL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-01-02 US disclosed
EP-0220810-A1 Insecticidal ethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-05-06 EP disclosed
EP-0160573-A2 Pyrimidinone derivatives NYCOMED AS (NO) 1985-11-06 EP disclosed