Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31337454 | 0.87 | GABRA1 (0.46) | TYRCYP1A2CYP2D6GABRA1GABRB2 | |
| SCHEMBL4755155 | 0.84 | GABRA1 (0.52) | TYRALOX5PTGS2CYP1A2CYP2D6 | |
| SCHEMBL13895963 | 0.81 | TYR (0.46) | EGFRTYRALOX5PTGS2GABRA1 | |
| SCHEMBL8037388 | 0.80 | TYR (0.42) | EGFRTYRALOX5PTGS2CYP2D6 | |
| SCHEMBL1023755 | 0.79 | HTT (0.46) | EGFRTYRALOX5PTGS2GABRA1 | |
| SCHEMBL1023152 | 0.79 | HPGD (0.52) | EGFRTYRALOX5PTGS2GABRA1 | |
| SCHEMBL30628001 | 0.79 | HPGD (0.52) | EGFRTYRALOX5PTGS2GABRA1 | |
| SCHEMBL1020399 | 0.79 | EGFR (0.44) | EGFRTYRALOX5PTGS2GABRA1 | |
| SCHEMBL872522 | 0.79 | EGFR (0.43) | EGFRTYRALOX5PTGS2GABRA1 | |
| SCHEMBL4854736 | 0.79 | EGFR (0.43) | EGFRTYRALOX5PTGS2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227111-A1 | TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF | Yoshitomi Fine Chemicals, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
| CN-1214067-A | Triphenylborane-rosin amine adduct and use of same | YOSHITAMI FINE CHEMICALS LTD (JP) | 1999-04-14 | — | — | CN | disclosed |
| EP-0877061-A1 | TRIPHENYLBORANE-ROSIN AMINE ADDUCT AND USE OF THE SAME | Yoshitomi Fine Chemicals, Ltd. (JP) | 1998-11-11 | — | — | EP | disclosed |