Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854736 | 0.90 | EGFR (0.43) | EGFRTYRALOX5FFAR1PTGS2 | |
| SCHEMBL11822461 | 0.85 | ALOX5 (0.43) | EGFRTYRALOX5PTGS2HCAR3 | |
| SCHEMBL13013439 | 0.85 | EGFR (0.48) | EGFRTYRALOX5FFAR1PTGS2 | |
| SCHEMBL1629294 | 0.84 | EGFR (0.41) | EGFRTYRALOX5FFAR1PTGS2 | |
| SCHEMBL13013000 | 0.83 | FFAR1 (0.43) | EGFRALOX5FFAR1PTGS2MEN1 | |
| SCHEMBL10272267 | 0.83 | ALOX5 (0.41) | EGFRTYRALOX5PTGS2MAOA | |
| SCHEMBL328706 | 0.83 | ALOX5 (0.41) | EGFRTYRALOX5PTGS2MAOA | |
| SCHEMBL872574 | 0.83 | EGFR (0.40) | EGFRTYRALOX5FFAR1PTGS2 | |
| SCHEMBL8444792 | 0.81 | EGFR (0.39) | EGFRTYRALOX5FFAR1PTGS2 | |
| SCHEMBL13180438 | 0.81 | TDP1 (0.40) | EGFRTYRALOX5FFAR1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143324-B2 | antioxidants with hindered phenol functionality perform better in curing of polybenzocyclobutene materials in air without undue degradation of key properties | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-03-27 | — | — | US | disclosed |
| US-20090275673-A1 | Benzocyclobutene based polymer formulations and methods for processing such formulations in oxidative environments | DOW GLOBAL TECHNOLOGIES LLC | 2009-11-05 | — | — | US | disclosed |