SCHEMBL4755155

SCHEMBL4755155

CCCCc1cc(C(C)C)cc(C(C)C)c1O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 5/20 0.52
GABRB2 P47870 3/20 0.52
FABP3 P05413 2/20 0.41
FABP4 P15090 2/20 0.41
FABP5 Q01469 1/20 0.41
TYR P14679 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ALOX5 P09917 4/20 0.38
PTGS2 P35354 3/20 0.37
GABRB1 P18505 4/20 0.37
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRA4 P48169 1/20 0.36
GABRA6 Q16445 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
GSR P00390 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7562102 0.84 EGFR (0.41) GABRA1GABRB2TYRALOX5PTGS2
SCHEMBL27527688 0.84 GABRA1 (0.42) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL11803468 0.82 GABRA1 (0.59) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL8897499 0.80 GABRA1 (0.61) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL7626430 0.79 TYR (0.37) TYRALOX5PTGS2CYP2D6
SCHEMBL14682849 0.78 GABRA1 (0.59) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL11805847 0.77 ALOX5 (0.45) TYRCA1CA2ALOX5PTGS2
SCHEMBL14705354 0.77 GABRA1 (0.57) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL14703867 0.77 GABRA1 (0.57) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL5588983 0.76 MAPK1 (0.42) TYRCA1CA2ALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101679701-B Use of nucleated propylene butene terpolymers for the production of sterilizable blown films BOREALIS TECH OY 2012-11-14 CN disclosed
EP-1960466-A1 A PROCESS FOR PRODUCING POLYOLEFIN MOLDED ARTICLES COMPRISING AN ETHYLENE-VINYL ALCOHOL COPOLYMER Basell Poliolefine Italia S.r.l. (IT) 2008-08-27 EP disclosed
WO-2007068536-A1 A PROCESS FOR PRODUCING POLYOLEFIN MOLDED ARTICLES COMPRISING AN ETHYLENE-VINYL ALCOHOL COPOLYMER BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2007-06-21 WO disclosed
EP-1664162-A1 POLYPROPYLENE BLOWN FILM Borealis Technology Oy (FI) 2006-06-07 EP disclosed
WO-2005026240-A1 POLYPROPYLENE BLOWN FILM BOREALIS TECHNOLOGY OY (FI) 2005-03-24 WO disclosed