SCHEMBL7562196

SCHEMBL7562196

CC(C)c1cc2ccccc2c2c1C=CC(c1ccc(N3CCOCC3)cc1)(c1ccc(N3CCOCC3)cc1)O2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 4/20 0.36
KDM4E B2RXH2 3/20 0.36
GAA P10253 3/20 0.36
HCRTR1 O43613 2/20 0.36
LMNA P02545 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
APAF1 O14727 1/20 0.35
CDC25B P30305 1/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
PIK3C2B O00750 1/20 0.35
MAPK1 P28482 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
HPGD P15428 1/20 0.34
SLC2A1 P11166 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8038479 0.98 AHR (0.38) AHRALDH1A1MAPTKDM4EGAA
SCHEMBL8036205 0.89 MAPT (0.32) AHRALDH1A1MAPTKDM4EGAA
SCHEMBL29756206 0.83 MEN1 (0.32) MEN1KMT2A
SCHEMBL5545747 0.83 MEN1 (0.32) MEN1KMT2A
SCHEMBL24620642 0.81 LMNA (0.41) AHRALDH1A1MAPTKDM4EGAA
SCHEMBL8509702 0.81 MEN1 (0.43) ALDH1A1MAPTKDM4EHCRTR1NPC1
SCHEMBL10102260 0.80 GPR84 (0.34)
SCHEMBL3824881 0.79 HTT (0.42) ALDH1A1MAPTKDM4ELMNAPIK3C2B
SCHEMBL7971543 0.78 KIF11 (0.40) AHRALDH1A1MAPTKDM4EGAA
SCHEMBL5550214 0.77 KMT2A (0.47) ALDH1A1MAPTKDM4EGAAHCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0940694-B1 Photochromic curable composition TOKUYAMA CORP (JP) 2002-08-14 EP disclosed
US-6194511-B1 COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND TOKUYAMA CORPORATION (JP) 2001-02-27 US disclosed
EP-0940694-A1 Photochromic curable composition TOKUYAMA CORPORATION (JP) 1999-09-08 EP disclosed