Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.54 |
| ▸ | TOP2A | P11388 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9781755 | 0.99 | LTA4H (0.53) | LTA4HTOP2AALDH1A1ALOX5CYP3A4 | |
| SCHEMBL1749601 | 0.94 | ALDH1A1 (0.55) | LTA4HTOP2AALDH1A1ALOX5CYP3A4 | |
| SCHEMBL18241200 | 0.91 | LTA4H (0.51) | LTA4HTOP2AALDH1A1ALOX5PPID | |
| SCHEMBL21559798 | 0.82 | HTT (0.72) | LTA4HTOP2AALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL27401224 | 0.82 | HDAC3 (0.54) | LTA4HTOP2AALDH1A1ALOX5CYP3A4 | |
| SCHEMBL24768581 | 0.82 | ALDH1A1 (0.58) | LTA4HTOP2AALDH1A1ALOX5CYP3A4 | |
| SCHEMBL9504635 | 0.82 | HTT (0.62) | ALDH1A1CYP2C19HDAC3HDAC4HDAC1 | |
| SCHEMBL28016562 | 0.82 | ALDH1A1 (0.58) | LTA4HTOP2AALDH1A1ALOX5CYP3A4 | |
| SCHEMBL9069760 | 0.81 | HTT (0.44) | LTA4HALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1375075 | 0.81 | HDAC3 (0.60) | LTA4HALDH1A1ALOX5CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002070545-A2 | SIDEROPHORE ANALOGUES AS TETRA- OR HEXADENTATE IRON CHELATORS ON THE BASIS OF AMINO ACIDS OR PEPTIDES, METHOD FOR PRODUCING THEM AND THE USE THEREOF | Grünenthal GmbH (DE) | 2002-09-12 | — | — | WO | disclosed |