Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | MC3R | P41968 | 8/20 | 0.39 |
| ▸ | MC4R | P32245 | 7/20 | 0.39 |
| ▸ | MC1R | Q01726 | 7/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6042959 | 0.90 | MCHR1 (0.41) | MCHR1MC3RMC4RMC1RTACR1 | |
| SCHEMBL6042963 | 0.90 | MCHR1 (0.41) | MCHR1MC3RMC4RMC1RTACR1 | |
| SCHEMBL6043085 | 0.90 | MCHR1 (0.41) | MCHR1MC3RMC4RMC1RTACR1 | |
| SCHEMBL6044726 | 0.88 | MCHR1 (0.42) | MCHR1MC3RMC4RMC1RTACR1 | |
| SCHEMBL6044326 | 0.88 | MCHR1 (0.42) | MCHR1MC3RMC4RMC1RTACR1 | |
| SCHEMBL6042254 | 0.88 | MCHR1 (0.42) | MCHR1MC3RMC4RMC1RTACR1 | |
| SCHEMBL7562673 | 0.77 | FAAH (0.46) | MCHR1MC3RMC4RMC1RSLC18A3 | |
| SCHEMBL6042262 | 0.70 | FAAH (0.43) | MCHR1SLC18A3ALDH1A1GAAMAPT | |
| SCHEMBL6042950 | 0.70 | CCR1 (0.44) | MCHR1TACR1CCR3ALDH1A1GAA | |
| Trifluoroacetic Acid SCHEMBL6041683 | 0.70 | REN (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |