Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.46 |
| ▸ | CCR1 | P32246 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | MC3R | P41968 | 2/20 | 0.40 |
| ▸ | MC1R | Q01726 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6042950 | 0.89 | CCR1 (0.44) | FAAHCCR1ALDH1A1GAAMAPT | |
| SCHEMBL6042262 | 0.87 | FAAH (0.43) | FAAHCCR1ALDH1A1GAAMAPT | |
| SCHEMBL7562668 | 0.77 | MCHR1 (0.40) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2928091 | 0.69 | FAAH (0.59) | FAAHMAPTSMN1; SMN2MCHR1HRH3 | |
| SCHEMBL6043085 | 0.69 | MCHR1 (0.41) | CCR1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL6042959 | 0.69 | MCHR1 (0.41) | CCR1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL6042963 | 0.69 | MCHR1 (0.41) | CCR1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL7745919 | 0.69 | FAAH (0.55) | FAAHCCR1ALDH1A1GAAMAPT | |
| SCHEMBL6044326 | 0.68 | MCHR1 (0.42) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6044726 | 0.68 | MCHR1 (0.42) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |