Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.52 |
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16799143 | 0.84 | PDE4B (0.47) | FAAHMAPTPDE4BPDE4APDE4C | |
| SCHEMBL31073550 | 0.84 | KCNH2 (0.56) | RAB9ANPC1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18805528 | 0.84 | NAMPT (0.60) | FAAHMAPTSMN1; SMN2NAMPT | |
| SCHEMBL2594236 | 0.84 | NAMPT (0.60) | FAAHMAPTSMN1; SMN2NAMPT | |
| SCHEMBL22531787 | 0.83 | HSD11B1 (0.49) | MAPTCCR1PDE4BPDE4APDE4C | |
| SCHEMBL3312519 | 0.83 | PDE4B (0.45) | FAAHMAPTPDE4BPDE4APDE4C | |
| SCHEMBL10460507 | 0.82 | QDPR (0.62) | FAAHRAB9ANPC1MAPTPARP10 | |
| SCHEMBL28036178 | 0.82 | RAB9A (0.55) | FAAHRAB9ANPC1MAPTPARP10 | |
| SCHEMBL2636274 | 0.80 | RAB9A (0.57) | FAAHRAB9ANPC1MAPTPARP10 | |
| SCHEMBL1239651 | 0.79 | POLB (0.56) | FAAHMAPTPDE4BSMN1; SMN2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001029002-A1 | PROCESS FOR THE PREPARATION OF 4-(FLUOROPHENYL)PIPERIDINE ESTERS | SMITHKLINE BEECHAM PLC (GB) | 2001-04-26 | — | — | WO | disclosed |