Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872276 | 0.82 | NOS2 (0.38) | NOS2NOS3DYRK1ACYP2D6CYP2C19 | |
| SCHEMBL15306037 | 0.77 | NUDT1 (0.45) | MAPTNOS2NOS3HRH3HSP90AB1 | |
| SCHEMBL2876986 | 0.77 | HSP90AB1 (0.56) | MAPTHRH4HSP90AB1CYP2D6CYP2C19 | |
| SCHEMBL793240 | 0.77 | NOS2 (0.41) | NOS2NOS3NOS1 | |
| SCHEMBL656121 | 0.76 | MAPT (0.50) | MAPTTDP1NOS2NOS3HRH4 | |
| SCHEMBL7563064 | 0.76 | MAPT (0.36) | MAPTCCR1TDP1NOS2NOS3 | |
| SCHEMBL6361284 | 0.76 | NOS2 (0.59) | NOS2NOS3HRH4HRH3NOS1 | |
| Bromide SCHEMBL7564429 | 0.74 | MAPT (0.35) | MAPTCCR1TDP1NOS2NOS3 | |
| SCHEMBL11769384 | 0.74 | NOS2 (0.40) | NOS2NOS3DYRK1ANOS1 | |
| SCHEMBL21590377 | 0.73 | NOS2 (0.36) | MAPTCCR1TDP1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077981-B1 | NOVEL CEPHALOSPORIN COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME | LG CHEMICAL LTD (KR) | 2002-08-07 | — | — | EP | disclosed |
| CN-1300290-A | Novel cephalosporin compounds, process for their preparation and antibacterial compositions containing them | LG CHEMICAL LTD (KR) | 2001-06-20 | — | — | CN | disclosed |
| EP-1077981-A1 | NOVEL CEPHALOSPORIN COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME | LG CHEMICAL LIMITED (KR) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058535-A1 | NOVEL CEPHALOSPORIN COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME | LG CHEMICAL LTD. (KR) | 1999-11-18 | — | — | WO | disclosed |