Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 3/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6041417 | 0.80 | PDCD1 (0.41) | FFAR1KCNH2FFAR4RENMET | |
| SCHEMBL7563846 | 0.79 | CYP3A4 (0.33) | KCNH2REN | |
| SCHEMBL7560414 | 0.79 | MAPT (0.43) | FFAR1REN | |
| SCHEMBL7560322 | 0.77 | REN (0.39) | KCNH2ADAM17MAOBREN | |
| SCHEMBL7566308 | 0.76 | REN (0.37) | MAOBRENYAP1 | |
| SCHEMBL7563899 | 0.76 | REN (0.37) | MAOBRENYAP1 | |
| SCHEMBL7562108 | 0.76 | SLC6A4 (0.39) | KCNH2REN | |
| SCHEMBL6041828 | 0.74 | REN (0.48) | FFAR1KCNH2FFAR4RENPDCD1 | |
| SCHEMBL7561346 | 0.74 | SLC6A4 (0.38) | KCNH2 | |
| SCHEMBL7569293 | 0.74 | TACR1 (0.41) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |