Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3104384 | 0.80 | CES2 (0.45) | CES2ABHD16ACYP1A2GRM2POLB | |
| SCHEMBL7559916 | 0.79 | CES2 (0.52) | CES2ABHD16ACYP1A2POLBFASN | |
| SCHEMBL11954843 | 0.77 | CES2 (0.43) | CES2ABHD16ACYP1A2GRM2POLB | |
| SCHEMBL15598670 | 0.77 | ABHD16A (0.48) | CES2ABHD16ACYP1A2GRM2POLB | |
| SCHEMBL15598671 | 0.77 | ABHD16A (0.48) | CES2ABHD16ACYP1A2GRM2POLB | |
| SCHEMBL18784042 | 0.77 | ABHD16A (0.48) | CES2ABHD16ACYP1A2GRM2POLB | |
| SCHEMBL16639647 | 0.77 | ABHD16A (0.48) | CES2ABHD16ACYP1A2GRM2POLB | |
| SCHEMBL5674415 | 0.77 | ABHD16A (0.48) | CES2ABHD16ACYP1A2GRM2POLB | |
| SCHEMBL16639646 | 0.75 | ABHD16A (0.46) | CES2ABHD16ACYP1A2GRM2POLB | |
| SCHEMBL18784040 | 0.75 | ABHD16A (0.46) | CES2ABHD16ACYP1A2GRM2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223168-A1 | Method for the preparation of enantiomerically enriched amino and hydroxyfuranones | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2002-07-17 | — | — | EP | disclosed |