Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA7 | P43166 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817678 | 0.70 | TSHR (0.43) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL819237 | 0.69 | TSHR (0.50) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL818676 | 0.68 | LMNA (0.44) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL22084581 | 0.68 | CA12 (0.39) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL47924 | 0.64 | CA12 (0.42) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL9735115 | 0.64 | CYP1A2 (0.41) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL5504594 | 0.64 | MAPT (0.37) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL9735228 | 0.63 | CYP1A2 (0.40) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL7288909 | 0.63 | CYP1A2 (0.43) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL4467924 | 0.62 | ALDH1A1 (0.41) | TSHRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350875-B1 | COMPOUNDS FOR ELECTRONICS | THE UNIVERSITY OF SOUTHERN CALIFORNIA | 2002-02-26 | — | — | US | disclosed |
| US-20020016474-A1 | Synthesis of cyclooctatetraene derivatives and their use as electron transporters in organic light emitting diodes | WEBER WILLIAM P (US) | 2002-02-07 | — | — | US | disclosed |
| WO-2001012576-A1 | SYNTHESIS OF CYCLOOCTATETRAENE DERIVATIVES AND THEIR USE AS ELECTRON TRANSPORTERS IN ORGANIC LIGHT EMITTING DIODES | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2001-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016474-A1 | Synthesis of cyclooctatetraene derivatives and their use as electron transporters in organic light emitting diodes | SLC18A3, SLC18A2, SLC25A21 | TSHR 3825/4885CA12 3570/4885CA1 4367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.