SCHEMBL7563367

SCHEMBL7563367

OCCOCCNc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 3/20 0.64
ALDH1A1 P00352 5/20 0.50
MAPT P10636 3/20 0.50
RAB9A P51151 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
LMNA P02545 1/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 2/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 1/20 0.44
AURKA O14965 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
RECQL P46063 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MCL1 Q07820 1/20 0.41
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9526296 0.98 KCNH3 (0.62) KCNH3ALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL3248804 0.89 ALDH1A1 (0.61) KCNH3ALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL15455346 0.81 KCNH3 (0.47) KCNH3ALDH1A1MAPTRAB9AKDM4E
SCHEMBL4848681 0.81 KCNH3 (0.50) KCNH3ALDH1A1MAPTRAB9AKDM4E
SCHEMBL7931717 0.80 ALDH1A1 (0.50) KCNH3ALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL4854821 0.79 KCNH3 (0.49) KCNH3ALDH1A1MAPTRAB9AKDM4E
SCHEMBL8063231 0.79 ALDH1A1 (0.53) KCNH3ALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL25192583 0.78 ALDH1A1 (0.48) KCNH3ALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL9015900 0.78 KCNH3 (0.51) KCNH3ALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL14982724 0.78 KCNH3 (0.51) KCNH3ALDH1A1MAPTRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5948268-A DISSOLVING IN WATER TO BE TREATED A POLYMER FORMED FROM WATER SOLUBLE MONOMER UNITS COMPRISING A (POLY)ALKYLENE OXIDE END CAPPED WITH AN ADDITION POLYMERIZABLE GROUP AT ONE END AND AN INTENSELY FLUORESCENT GROUP AT OTHER NIPPON SHOKUBAI CO., LTD. (JP) 1999-09-07 US claimed
EP-2968381-A1 SUGAR-LINKER-DRUG CONJUGATES Hecht, Sidney (US) 2016-01-20 EP disclosed
WO-2014145109-A1 SUGAR-LINKER-DRUG CONJUGATES ARIZONA BOARD OF REGENTS, FOR AND ON BEHALF OF, ARIZONA STATE UNIVERSITY (US) 2014-09-18 WO disclosed
WO-2012118939-A1 INSULATIVE PRODUCTS HAVING BIO-BASED BINDERS OWENS CORNING INTELLECTUAL CAPITAL, LLC (US) 2012-09-07 WO disclosed
US-6398944-B1 OXIDATION OF ACIDS FORMED BY ELECTRODEPOSITION OF FILM-FORMING CATIONIC POLYMERS, USING ANODES COATED WITH A CATALYTIC LAYER OF TIN OXIDE OR MIXTURES OF TIN OXIDE WITH RUTHENIUM OR IRIDIUM OXIDES BASF COATINGS AG (DE) 2002-06-04 US disclosed
US-20020060155-A1 Method of removing acid formed during cathodic electrodip coatings ARLT KLAUS (DE) 2002-05-23 US disclosed
EP-0761604-B1 An agent for water treatment NIPPON CATALYTIC CHEM IND (JP) 2000-06-14 EP disclosed
US-5948268-A DISSOLVING IN WATER TO BE TREATED A POLYMER FORMED FROM WATER SOLUBLE MONOMER UNITS COMPRISING A (POLY)ALKYLENE OXIDE END CAPPED WITH AN ADDITION POLYMERIZABLE GROUP AT ONE END AND AN INTENSELY FLUORESCENT GROUP AT OTHER NIPPON SHOKUBAI CO., LTD. (JP) 1999-09-07 US disclosed
EP-0517245-B1 Developer for light-sensitive material DAINIPPON INK & CHEMICALS (JP) 1998-02-11 EP disclosed
EP-0761604-A2 An agent for water treatment NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-12 EP disclosed
EP-0441222-B1 Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds BOEHRINGER MANNHEIM GMBH (DE) 1996-12-18 EP disclosed
US-5286362-A Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially BOEHRINGER MANNHEIM GMBH (DE) 1994-02-15 US disclosed
US-5275915-A Alkali metal compounds with anionic surfactant and antifoggant for silver halide photographic films DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-01-04 US disclosed
EP-0301751-B1 PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1993-03-10 EP disclosed
EP-0517245-A1 Developer for light-sensitive material DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-12-09 EP disclosed
US-5122244-A Having a reducible nitroso or oxime compound to transfer electrons leading to a signal and form an aromatic amine oxidizable to a compound different from the original; low voltage BOEHRINGER MANNHEIM GMBH (DE) 1992-06-16 US disclosed
EP-0441222-A2 Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds Roche Diagnostics GmbH (DE) 1991-08-14 EP disclosed
US-4962113-A PLATELET ACTIVATING FACTOR ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD (JP) 1990-10-09 US disclosed
EP-0301751-A1 Pyridinium derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-01 EP disclosed