SCHEMBL3248804

SCHEMBL3248804

c1ccc(NCCOCCNc2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
MAPT P10636 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.52
KCNH3 Q9ULD8 4/20 0.50
LMNA P02545 2/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.44
F2 P00734 1/20 0.41
HRH3 Q9Y5N1 1/20 0.40
CTSD P07339 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7931717 0.89 ALDH1A1 (0.50) ALDH1A1MAPTL3MBTL1KCNH3LMNA
SCHEMBL7563367 0.89 KCNH3 (0.64) ALDH1A1MAPTL3MBTL1KCNH3LMNA
SCHEMBL30462887 0.88 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1KCNH3LMNA
SCHEMBL9526296 0.88 KCNH3 (0.62) ALDH1A1MAPTL3MBTL1KCNH3LMNA
SCHEMBL30462888 0.88 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1KCNH3LMNA
SCHEMBL25192583 0.88 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1KCNH3LMNA
SCHEMBL9015900 0.88 KCNH3 (0.51) ALDH1A1MAPTL3MBTL1KCNH3LMNA
SCHEMBL19628899 0.88 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1KCNH3LMNA
SCHEMBL14982724 0.88 KCNH3 (0.51) ALDH1A1MAPTL3MBTL1KCNH3LMNA
SCHEMBL26815529 0.88 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1KCNH3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111650811-B White photosensitive film and preparation method and application thereof 上海孚赛特新材料股份有限公司 2024-01-26 CN disclosed
US-20190125699-A1 TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN CIPHER PHARMACEUTICALS INC. (CA) 2019-05-02 US disclosed
CN-104020622-B Display particle, display particle dispersion, display medium and display device 电子墨水公司 2018-07-24 CN disclosed
US-9907765-B2 Treatment of connective tissue diseases of the skin CIPHER PHARMACEUTICALS INC. (CA) 2018-03-06 US disclosed
US-20170157068-A1 TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN ASTION PHARMA A/S (DK) 2017-06-08 US disclosed
US-20130237607-A1 TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN ASTION DEVELOPMENT A/S (DK) 2013-09-12 US disclosed
US-8426475-B2 Treatment of connective tissue diseases of the skin ASTION DEVELOPMENT A/S (DK) 2013-04-23 US disclosed
EP-1719507-B1 Beta-2 adrenoceptor agonists for treating connective tissue diseases of the skin ASTION DEV AS (DK) 2010-07-14 EP disclosed
WO-2006108424-A9 BETA-2 ADRENOCEPTOR AGONISTS FOR TREATING CONNECTIVE TISSUE DISEASES OF THE SKIN ASTION DEV AS (DK) 2007-08-09 WO disclosed
EP-1719507-A1 Beta-2 adrenoceptor agonists for treating connective tissue diseases of the skin Astion Development A/S (DK) 2006-11-08 EP disclosed
EP-1496917-A1 COMBINATION OF A BETA-2 ADRENOCEPTOR AGONISTS AND AN AMINOSUGARS AND THEIR USE FOR THE TREATMENT IMMUNOMODULATORY DISORDERS Astion Development APS (DK) 2005-01-19 EP disclosed
WO-2003097073-A1 COMBINATION OF A BETA-2 ADRENOCEPTOR AGONISTS AND AN AMINOSUGARS AND THEIR USE FOR THE TREATMENT IMMUNOMODULATORY DISORDERS ASTION DEVELOPMENT A/S (DK) 2003-11-27 WO disclosed
US-6525150-B1 Such as vanadium 2,2'-thiobis(6-t-butyl-4-methylphenyl) oxychloride complex, trimethylaluminum and N,N-dimethyl-anilinium tetrakis(pentafluorophenyl)borate; high degree of copolymerization JSR CORPORATION (JP) 2003-02-25 US disclosed
EP-1046654-A1 Olefin polymerization catalysts and olefin polymer production methods using said olefin polymerization catalysts JSR Corporation (JP) 2000-10-25 EP disclosed
WO-1995019336-A1 PHENYL ETHANOL AMINE ETHERS AND USES THEREOF AS β-ADRENO-RECEPTOR AGONISTS IOVIS BIOMEDICAL AND PHARMACEUTICAL CONSULTANTS (NL) 1995-07-20 WO disclosed
EP-0308745-B1 THICKENED MOULDING COMPOSITION BASF Aktiengesellschaft (DE) 1992-11-19 EP disclosed
US-5047455-A Containing liquid, polymerizable reactive system, isocyanate, initiator and additive shelf life BASF AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0308745-A2 Thickened moulding composition BASF Aktiengesellschaft (DE) 1989-03-29 EP disclosed
US-4095022-A PHOSPHORUS COMPOUNDS, SILICA-ALUMINA CATALYST TEXACO DEVELOPMENT CORPORATION (US) 1978-06-13 US disclosed
US-4026935-A FROM N-(HYDROXYALKYL)-MORPHOLINE COMPOUND, SILICA-ALUMINA CATALYST TEXACO DEVELOPMENT CORPORATION (US) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130237607-A1 TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN ADRB2, ADRB1, ADRA2A ALDH1A1 1389/4885MAPT 3107/4885L3MBTL1 2856/4885
US-20170157068-A1 TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN ADRB2, ADRB1, ADRA2A ALDH1A1 1389/4885MAPT 3107/4885L3MBTL1 2856/4885
US-20190125699-A1 TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN ADRB2, ADRB1, ADRA2A ALDH1A1 1389/4885MAPT 3107/4885L3MBTL1 2856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.