Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563412 | 1.00 | REN (0.34) | RENCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7567638 | 0.84 | REN (0.48) | REN | |
| SCHEMBL7567650 | 0.84 | REN (0.48) | REN | |
| SCHEMBL6041436 | 0.83 | REN (0.44) | REN | |
| SCHEMBL6041428 | 0.83 | REN (0.44) | REN | |
| SCHEMBL6041280 | 0.81 | REN (0.35) | REN | |
| SCHEMBL6041282 | 0.81 | REN (0.35) | REN | |
| SCHEMBL7563899 | 0.79 | REN (0.37) | REN | |
| SCHEMBL7566308 | 0.79 | REN (0.37) | REN | |
| SCHEMBL7560414 | 0.77 | MAPT (0.43) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |