Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043959 | 0.79 | REN (0.78) | REN | |
| SCHEMBL7595673 | 0.79 | TLR9 (0.36) | — | |
| SCHEMBL6041383 | 0.78 | TEAD3 (0.36) | — | |
| Bicarbonate SCHEMBL7434636 | 0.77 | REN (0.61) | REN | |
| SCHEMBL16885978 | 0.76 | MAOB (0.58) | REN | |
| SCHEMBL16874773 | 0.76 | MAOB (0.58) | REN | |
| SCHEMBL7566213 | 0.75 | REN (0.63) | REN | |
| Hydrochloric Acid SCHEMBL16874669 | 0.75 | MAOB (0.57) | REN | |
| Hydrochloric Acid SCHEMBL28261567 | 0.75 | MAOB (0.57) | REN | |
| SCHEMBL6043117 | 0.75 | REN (0.80) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |