Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | GRK2 | P25098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563503 | 0.79 | REN (0.49) | — | |
| SCHEMBL6042417 | 0.79 | REN (0.37) | TLR9TLR8TLR7 | |
| SCHEMBL25298244 | 0.73 | KDM4E (0.40) | — | |
| SCHEMBL6041437 | 0.72 | REN (0.39) | TLR9TLR8TLR7GRK2 | |
| SCHEMBL6042056 | 0.71 | MEN1 (0.34) | — | |
| SCHEMBL6043929 | 0.70 | KDM1A (0.52) | — | |
| SCHEMBL19097411 | 0.70 | ESR2 (0.41) | TLR9TLR8TLR7GRK2 | |
| SCHEMBL8193235 | 0.70 | ESR2 (0.41) | TLR9TLR8TLR7GRK2 | |
| SCHEMBL6042043 | 0.70 | ESR2 (0.41) | TLR9TLR8TLR7GRK2 | |
| SCHEMBL7445147 | 0.69 | TLR9 (0.36) | TLR9TLR8TLR7ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |