Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22242828 | 0.98 | KCNH2 (0.48) | HSD17B10CYP1A2CYP2C9HPGDMAPK1 | |
| SCHEMBL27511565 | 0.98 | KCNH2 (0.48) | HSD17B10CYP1A2CYP2C9HPGDMAPK1 | |
| SCHEMBL4452042 | 0.98 | KCNH2 (0.48) | HSD17B10CYP1A2CYP2C9HPGDMAPK1 | |
| SCHEMBL1404105 | 0.98 | KCNH2 (0.48) | HSD17B10CYP1A2CYP2C9HPGDMAPK1 | |
| SCHEMBL8750318 | 0.98 | KCNH2 (0.48) | HSD17B10CYP1A2CYP2C9HPGDMAPK1 | |
| Ammonia Solution, Strong SCHEMBL6253711 | 0.98 | HSD17B10 (0.47) | HSD17B10CYP1A2CYP2C9HPGDMAPK1 | |
| SCHEMBL465391 | 0.98 | KCNH2 (0.48) | HSD17B10CYP1A2CYP2C9HPGDMAPK1 | |
| SCHEMBL1532514 | 0.98 | KCNH2 (0.48) | HSD17B10CYP1A2CYP2C9HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL27703679 | 0.95 | KCNH2 (0.47) | HSD17B10CYP1A2CYP2C9HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL28013071 | 0.95 | KCNH2 (0.47) | HSD17B10CYP1A2CYP2C9HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647677-B2 | Analogues of hydroxychloroquine (HCQ) without retinal toxicity | INOVIEM SCIENTIFIC (FR) | 2020-05-12 | — | — | US | disclosed |
| EP-2860170-B1 | PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE | OSAKA ORGANIC CHEMICAL IND LTD (JP) | 2019-08-28 | — | — | EP | disclosed |
| WO-2019155016-A1 | VIRAL VECTOR TRANSDUCTION | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2019-08-15 | — | — | WO | disclosed |
| EP-3015449-B1 | (METH)ACRYLATE PRODUCTION SYSTEM | OSAKA ORGANIC CHEMICAL IND LTD (JP) | 2018-10-10 | — | — | EP | disclosed |
| CN-105339341-B | Production system for (meth) acrylic acid ester | 大阪有机化学工业株式会社 | 2018-02-13 | — | — | CN | disclosed |
| US-9670129-B2 | Process for preparing 4-hydroxybutyl acrylate | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2017-06-06 | — | — | US | disclosed |
| US-20160136538-A1 | (METH)ACRYLATE PRODUCTION SYSTEM | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2016-05-19 | — | — | US | disclosed |
| EP-3015449-A1 | (METH)ACRYLATE PRODUCTION SYSTEM | Osaka Organic Chemical Ind., Ltd. (JP) | 2016-05-04 | — | — | EP | disclosed |
| CN-105339341-A | Production system for (meth) acrylic acid ester | OSAKA ORGANIC CHEM IND | 2016-02-17 | — | — | CN | disclosed |
| US-20150126766-A1 | PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2015-05-07 | — | — | US | disclosed |
| EP-2860170-A1 | PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE | Osaka Organic Chemical Ind., Ltd. (JP) | 2015-04-15 | — | — | EP | disclosed |
| CN-104220413-A | Method for producing 4-hydroxybutyl acrylate | OSAKA ORGANIC CHEM IND | 2014-12-17 | — | — | CN | disclosed |
| EP-0906902-B1 | A method for the production of an alkylamino (meth)acrylate and apparatus therefor. | NIPPON CATALYTIC CHEM IND (JP) | 2002-08-28 | — | — | EP | disclosed |
| US-6417392-B1 | CATALYTIC ESTER INTERCHANGE OF ALKYL (METH)ACRYLATE AND ALKYLAMINO ALCOHOL; DISTILLATION OF ALKYL ALCOHOL BY-PRODUCT IN AZEOTROPIC MIXTURE WITH ALKYL (METH)ACRYLATE; PURIFICATION USING ION EXCHANGE RESIN | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-07-09 | — | — | US | disclosed |
| EP-0906902-A2 | A method for the production of an alkylamino (meth)acrylate and apparatus therefor. | NIPPON SHOKUBAI CO., LTD. (JP) | 1999-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647677-B2 | Analogues of hydroxychloroquine (HCQ) without retinal toxicity | SSB, UACA, XPA | HSD17B10 1229/4885CYP1A2 1963/4885CYP2C9 486/4885 |
| US-20150126766-A1 | PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE | LTB4R2, LTA4H, LTB4R | HSD17B10 16/4885CYP1A2 123/4885CYP2C9 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.