SCHEMBL7563558

SCHEMBL7563558

Nc1nc(C(F)F)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31293113 0.87
SCHEMBL1617690 0.77 KDM4E (0.32)
SCHEMBL11733090 0.77 CASP1 (0.33)
SCHEMBL1977554 0.75
SCHEMBL9076886 0.71 CASP1 (0.33)
SCHEMBL9151003 0.71 TSHR (0.39)
SCHEMBL22556877 0.71 ALDH1A1 (0.32)
SCHEMBL10709901 0.67 HSP90AB1 (0.41)
SCHEMBL4536844 0.65
SCHEMBL2327692 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6413911-B1 REACTING A SULFONYL ISOCYANATE WITH A 2-AMINO-1,3,5-TRIAZINE OR 2-AMINOPYRIMIDINE, OR REACTING A SULFONAMIDE WITH A PHENYL CARBAMATE OR ISOCYANATE OF -1,3,5-TRIAZINE OR PYRIDINE BASF AKTIENGESELLSCHAFT (DE) 2002-07-02 US disclosed
US-20020049321-A1 Herbicidal sulfonylureas, their preparation and use MAYER HORST (DE) 2002-04-25 US disclosed
US-6320046-B1 A 2-AMINO-1,3,5-TRIAZINE AS CHEMICAL INTERMEDIATE; HIGH SELECTIVITY IN SENSITIVE CROPS BASF AKTIENGESELLSCHAFT (DE) 2001-11-20 US disclosed
US-6043196-A Herbicidal sulfonylureas, their preparation and use BASF AKTIENGESELLSCHAFT (DE) 2000-03-28 US disclosed
EP-0668858-B1 SULPHONYL UREA COMPOUNDS WITH A HERBICIDAL ACTION, METHOD OF PREPARING THEM AND THEIR USE BASF AG (DE) 1997-01-08 EP disclosed
EP-0668858-A1 SULPHONYL UREA COMPOUNDS WITH A HERBICIDAL ACTION, METHOD OF PREPARING THEM AND THEIR USE. BASF AG (DE) 1995-08-30 EP disclosed
WO-1994011358-A1 SULPHONYL UREA COMPOUNDS WITH A HERBICIDAL ACTION, METHOD OF PREPARING THEM AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 1994-05-26 WO disclosed