Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124929 | 0.80 | RAB9A (0.69) | RAB9AMEN1KMT2ATHRBSLC2A1 | |
| SCHEMBL7564779 | 0.78 | RXRA (0.50) | RAB9AMEN1KMT2AHPGDRECQL | |
| SCHEMBL8116657 | 0.76 | HPGD (0.43) | RAB9AMEN1KMT2AHPGDRECQL | |
| SCHEMBL7565539 | 0.76 | RXRA (0.42) | RAB9AHPGDRECQLMAPTNPC1 | |
| SCHEMBL9644563 | 0.76 | RAB9A (0.63) | RAB9AMEN1KMT2ATHRBSLC2A1 | |
| SCHEMBL28141853 | 0.75 | RAB9A (0.67) | RAB9AMEN1KMT2ATHRBSLC2A1 | |
| SCHEMBL6086102 | 0.75 | MEN1 (0.47) | RAB9AMEN1KMT2ATHRBSLC2A1 | |
| SCHEMBL7565083 | 0.75 | RAB9A (0.47) | RAB9AMEN1KMT2ATHRBSLC2A1 | |
| SCHEMBL9176722 | 0.74 | SMN1; SMN2 (0.72) | RAB9AMEN1KMT2ATHRBSLC2A1 | |
| SCHEMBL7570193 | 0.74 | RAB9A (0.47) | RAB9AMEN1KMT2ATHRBSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228055-A1 | DIHYDROAMINOBENZO[B]- AND [C]FURANS AS RETINOID-LIKE AGENTS | Allergan Sales, Inc. (US) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001012618-A1 | DIHYDROAMINOBENZO[B]- AND [C]FURANS AS RETINOID-LIKE AGENTS | ALLERGAN SALES, INC. (US) | 2001-02-22 | — | — | WO | disclosed |
| US-6093838-A | FOR TREATING SKIN-RELATED DISEASES, INCLUDING ACTINIC KERATOSES, ARSENIC KERATOSES, ECZEMA | ALLERGAN SALES, INC. (US) | 2000-07-25 | — | — | US | disclosed |