Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565961 | 0.89 | CYP1A2 (0.32) | GABRG2GABRB3GABRA5 | |
| SCHEMBL5952691 | 0.87 | MAOA (0.33) | MAOA | |
| SCHEMBL7565115 | 0.84 | MAOA (0.33) | MAOA | |
| SCHEMBL7571196 | 0.83 | MAOA (0.31) | MAOA | |
| Hydrochloric Acid SCHEMBL7564075 | 0.83 | GABRG2 (0.32) | GABRG2GABRB3GABRA5MAOAGABRA1 | |
| SCHEMBL5953054 | 0.82 | ADRA1A (0.32) | — | |
| SCHEMBL8361381 | 0.79 | — | — | |
| SCHEMBL8676204 | 0.78 | GABRG2 (0.33) | GABRG2GABRB3GABRA5MAOAGABRA1 | |
| SCHEMBL7566859 | 0.77 | CYP1A2 (0.32) | — | |
| SCHEMBL7565550 | 0.77 | MAOA (0.31) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840947-A | Organometallic compound | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | claimed |
| EP-0743317-B1 | Metallocenes comprising a heterocycle and catalysts containing them | BASELL POLYOLEFINE GMBH (DE) | 2002-08-28 | — | — | EP | disclosed |
| US-5840947-A | Organometallic compound | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0743317-A2 | Metallocenes comprising a heterocycle and catalysts containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-20 | — | — | EP | disclosed |