SCHEMBL7564159

SCHEMBL7564159

Oc1cccc(Nc2nc(Nc3cccc(O)c3)nc(Nc3cccc(O)c3)n2)c1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SYK P43405 8/20 0.64
CYP3A4 P08684 1/20 0.63
TSHR P16473 1/20 0.63
HDAC6 Q9UBN7 1/20 0.62
KMT2A Q03164 2/20 0.58
MEN1 O00255 1/20 0.56
POLB P06746 1/20 0.56
RAD52 P43351 1/20 0.56
GFER P55789 1/20 0.56
RAPGEF4 Q8WZA2 1/20 0.53
RHOA P61586 1/20 0.53
TAAR1 Q96RJ0 1/20 0.51
VSIR Q9H7M9 1/20 0.49
ADORA2A P29274 1/20 0.49
ADORA1 P30542 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22356493 0.98 SYK (0.62) SYKCYP3A4TSHRHDAC6KMT2A
SCHEMBL29819598 0.94 CYP3A4 (0.74) SYKCYP3A4TSHRHDAC6KMT2A
SCHEMBL12513290 0.94 CYP3A4 (0.74) SYKCYP3A4TSHRHDAC6KMT2A
SCHEMBL1318687 0.91 SYK (0.63) SYKCYP3A4TSHRHDAC6KMT2A
SCHEMBL3809017 0.91 SYK (0.55) SYKCYP3A4TSHRHDAC6KMT2A
SCHEMBL28888084 0.90 SYK (0.58) SYKCYP3A4TSHRHDAC6KMT2A
SCHEMBL4568691 0.89 NFKB1 (0.63) SYKCYP3A4TSHRHDAC6KMT2A
SCHEMBL657020 0.88 SYK (0.72) SYKCYP3A4TSHRHDAC6KMT2A
SCHEMBL23868692 0.88 SYK (0.55) SYKCYP3A4TSHRHDAC6KMT2A
SCHEMBL11616820 0.87 SYK (0.55) SYKCYP3A4TSHRHDAC6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189892-A1 MELAMINE DERIVATIVES AS POTENT ANTI-CANCER AGENTS Parker Hughes Institute (US) 2002-03-27 EP claimed
US-6262053-B1 EFFECTIVE FOR TREATING TUMOR CELLS AND PARTICULARLY EFFECTIVE TO INDUCE APOPTOSIS IN LEUKEMIA AND BREAST TUMOR CELLS. PARKER HUGHES INSTITUTE 2001-07-17 US claimed
WO-2000078738-A1 MELAMINE DERIVATIVES AS POTENT ANTI-CANCER AGENTS PARKER HUGHES INSTITUTE (US) 2000-12-28 WO claimed
CN-111065628-B Novel triazine derivative and photosensitive composition comprising the same 株式会社特雷尔 2023-06-02 CN disclosed
US-20230020941-A1 COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, THERMALLY CONDUCTIVE SHEET, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM CORPORATION (JP) 2023-01-19 US disclosed
US-11427551-B2 Triazine derivative and photosensitive composition comprising same TREEEL CO., LTD (KR) 2022-08-30 US disclosed
US-20220216126-A1 MANUFACTURING METHOD FOR THERMAL CONDUCTIVE LAYER, MANUFACTURING METHOD FOR LAMINATE, AND MANUFACTURING METHOD FOR SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2022-07-07 US disclosed
US-20220135861-A1 COMPOSITION FOR FORMING THERMALLY CONDUCTIVE MATERIAL, THERMALLY CONDUCTIVE MATERIAL, AND SURFACE-MODIFIED INORGANIC SUBSTANCE FUJIFILM CORPORATION (JP) 2022-05-05 US disclosed
US-20210301180-A1 COMPOSITION, THERMALLY CONDUCTIVE SHEET, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM CORPORATION (JP) 2021-09-30 US disclosed
US-20200262798-A1 NOVEL TRIAZINE DERIVATIVE AND PHOTOSENSITIVE COMPOSITION COMPRISING SAME TREEEL CO., LTD (KR) 2020-08-20 US disclosed
US-20200262798-A1 NOVEL TRIAZINE DERIVATIVE AND PHOTOSENSITIVE COMPOSITION COMPRISING SAME TREEEL CO., LTD (KR) 2020-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11427551-B2 Triazine derivative and photosensitive composition comprising same TYR, CRY2, CRY1 SYK 1366/4885CYP3A4 266/4885TSHR 2491/4885
US-20200262798-A1 NOVEL TRIAZINE DERIVATIVE AND PHOTOSENSITIVE COMPOSITION COMPRISING SAME TYR, CRY2, CRY1 SYK 1816/4885CYP3A4 322/4885TSHR 2861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.