Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569884 | 0.90 | ADRA1A (0.31) | ADRA1APDK2PDK4 | |
| SCHEMBL5952989 | 0.89 | ADRA1A (0.33) | ADRA1APDK2PDK4 | |
| SCHEMBL7571571 | 0.86 | KDM4E (0.30) | — | |
| SCHEMBL8677041 | 0.85 | P2RX7 (0.37) | — | |
| SCHEMBL217532 | 0.83 | — | — | |
| SCHEMBL7565550 | 0.83 | MAOA (0.31) | — | |
| SCHEMBL5952333 | 0.83 | CYP1A2 (0.31) | — | |
| SCHEMBL8674272 | 0.81 | P2RX7 (0.34) | — | |
| SCHEMBL5837000 | 0.81 | — | — | |
| SCHEMBL5951649 | 0.81 | EDNRB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840947-A | Organometallic compound | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | claimed |
| EP-0743317-B1 | Metallocenes comprising a heterocycle and catalysts containing them | BASELL POLYOLEFINE GMBH (DE) | 2002-08-28 | — | — | EP | disclosed |
| US-5840947-A | Organometallic compound | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0743317-A2 | Metallocenes comprising a heterocycle and catalysts containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-20 | — | — | EP | disclosed |